Liver hydrolysate assists in the recovery from physical fatigue in a mouse model.

摘要: Abstract It is reported that liver hydrolysate (LH) enhances function. However, the effects of LH on physical fatigue are unknown. The aim this study was to investigate effect alterations in locomotor activity and energy metabolism such as 5′-AMP-activated protein kinase (AMPK), glycogen content, blood lactic acid, after forced walking. Adult male ddY mice were used. Locomotor activity, AMPK phosphorylation, content soleus muscle, well acid determined following treatment before and/or significantly decreased walking for 3 h. Two administrations (30 or 100 mg/kg) increased while a single administration either did not show any specific effect. Administering twice activated muscle. Glycogen levels both muscle walking, whereas lactate level increased. In contrast, administering acid. These findings indicate produced an anti-fatigue appears involve efficient utilization through activation AMPK. [Supplementary Figure: available only at http://dx.doi.org/10.1254/jphs.13084FP ]