作者: Concepcion Prior , Serge Potier , Jean-Luc Souciet , Hana Sychrova
DOI: 10.1016/0014-5793(96)00470-X
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摘要: The NHA1 gene (2958 nt) encoding a putative Na(+)/H(+) antiporter (986 aa) in Saccharomyces cerevisiae was cloned by selection based on increased NaCl tolerance. protein is highly similar to sodium/proton antiporters from Schizosaccharomyces pombe (gene sod2), and Zygosaccharomyces rouxii Z-SOD2). Overexpression of the results higher partially pH-dependent tolerance sodium lithium; its disruption leads an sensitivity towards these ions.