Tissue interactions during skin histodifferentiation

摘要: Abstract Skin tissues from 11-day chick embryos have been cultured in protein-free nutrients. Under these conditions, epidermis displays columnar basal cells and mitoses only regions where an intimate junction is established with either dermis or muscle. Epidermis that fails to form a junction, alone, develops abnormally becomes necrotic by 4 days. Epidermal differentiation the tonofibril stage occurs epidermis-dermis recombinants of junction. The dermal-epidermal interaction can occur when Millipore filters are inserted between tissues, absence visualized periodic acid-Schiff staining at Intercellular materials randomly distributed dermal explants. In recombinants, usually appear first distant epidermis. Other properties interacting skin described, including some aspects scale morphogenesis.