Primed for the kill: occupying Bcl-2 to target death in acute myeloid leukaemia

作者: Andrew Wei , Tse-Chieh Teh

DOI: 10.7750/BIODISCOVERY.2012.6.1

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参考文章(33)
P Fenaux, P Jonveaux, I Quiquandon, JL Lai, JM Pignon, MH Loucheux-Lefebvre, F Bauters, R Berger, JP Kerckaert, P53 Gene Mutations in Acute Myeloid Leukemia With 17p Monosomy Blood. ,vol. 78, pp. 1652- 1657 ,(1991) , 10.1182/BLOOD.V78.7.1652.1652
T M Kohl, C Hellinger, F Ahmed, C Buske, W Hiddemann, S K Bohlander, K Spiekermann, BH3 mimetic ABT-737 neutralizes resistance to FLT3 inhibitor treatment mediated by FLT3-independent expression of BCL2 in primary AML blasts Leukemia. ,vol. 21, pp. 1763- 1772 ,(2007) , 10.1038/SJ.LEU.2404776
Kylie D. Mason, Cassandra J. Vandenberg, Clare L. Scott, Andrew H. Wei, Suzanne Cory, David C. S. Huang, Andrew W. Roberts, In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive Myc-driven lymphomas. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 105, pp. 17961- 17966 ,(2008) , 10.1073/PNAS.0809957105
Catherine C. Smith, Qi Wang, Chen-Shan Chin, Sara Salerno, Lauren E. Damon, Mark J. Levis, Alexander E. Perl, Kevin J. Travers, Susana Wang, Jeremy P. Hunt, Patrick P. Zarrinkar, Eric E. Schadt, Andrew Kasarskis, John Kuriyan, Neil P. Shah, Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia Nature. ,vol. 485, pp. 260- 263 ,(2012) , 10.1038/NATURE11016
Michael C Wei, Wei-Xing Zong, Emily H-Y Cheng, Tullia Lindsten, Vily Panoutsakopoulou, Andrea J Ross, Kevin A Roth, Grant R MacGregor, Craig B Thompson, Stanley J Korsmeyer, Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death Science. ,vol. 292, pp. 727- 730 ,(2001) , 10.1126/SCIENCE.1059108
Erinna F. Lee, Peter E. Czabotar, Mark F. van Delft, Ewa M. Michalak, Michelle J. Boyle, Simon N. Willis, Hamsa Puthalakath, Philippe Bouillet, Peter M. Colman, David C.S. Huang, W. Douglas Fairlie, A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation Journal of Cell Biology. ,vol. 180, pp. 341- 355 ,(2008) , 10.1083/JCB.200708096
Mark Levis, Farhad Ravandi, Eunice S. Wang, Maria R. Baer, Alexander Perl, Steven Coutre, Harry Erba, Robert K. Stuart, Michele Baccarani, Larry D. Cripe, Martin S. Tallman, Giovanna Meloni, Lucy A. Godley, Amelia A. Langston, Sergio Amadori, Ian D. Lewis, Arnon Nagler, Richard Stone, Karen Yee, Anjali Advani, Dan Douer, W. Wiktor-Jedrzejczak, Gunnar Juliusson, Mark R. Litzow, Stephen Petersdorf, Miguel Sanz, Hagop M. Kantarjian, Takashi Sato, Lothar Tremmel, Debra M. Bensen-Kennedy, Donald Small, B. Douglas Smith, Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse Blood. ,vol. 117, pp. 3294- 3301 ,(2011) , 10.1182/BLOOD-2010-08-301796
Cheuk Him Man, Tsz Kan Fung, Christa Ho, Heron H. C. Han, Howard C. H. Chow, Alvin C. H. Ma, William W. L. Choi, Si Lok, Alice M. S. Cheung, Connie Eaves, Yok Lam Kwong, Anskar Y. H. Leung, Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation. Blood. ,vol. 119, pp. 5133- 5143 ,(2012) , 10.1182/BLOOD-2011-06-363960
Twee Tsao, Yuexi Shi, Steven Kornblau, Hongbo Lu, Sergej Konoplev, Ansu Antony, Vivian Ruvolo, Yi Hua Qiu, Ninaxiang Zhang, Kevin R. Coombes, Michael Andreeff, Kensuke Kojima, Marina Konopleva, Concomitant inhibition of DNA methyltransferase and BCL-2 protein function synergistically induce mitochondrial apoptosis in acute myelogenous leukemia cells Annals of Hematology. ,vol. 91, pp. 1861- 1870 ,(2012) , 10.1007/S00277-012-1537-8