Intercellular Communication in Marine Vibrio Species: Density-Dependent Regulation of the Expression of Bioluminescence

摘要: This chapter focuses on the different molecular mechanisms two model luminous bacteria, Vibrio fischeri (a symbiont) and V. harveyi free-living microbe), use for regulating lux expression. Expression of luminescence in most bacteria is tightly regulated by density population. In fischeri, regulatory genes involved density-dependent control are adjacent to luxCDABEG operon encoding luciferase enzymes. The that from those fischeri. One complementation group dim mutants could be restored full light production a family recombinant cosmids containing subset common restriction fragments. Initial HAI-1 HAI-2 signal recognition LuxN LuxQ activate series phosphotransfer reactions. Two-component circuits have been characterized which single protein contains both sensor kinase response regulator domain (similar LuxQ) second DNA binding motif LuxO). differences between controlling expression striking. Subsequent mutations gene duplications rearrangements generated new multiple autoinducers, receptivities, connections, finally resulting bacterium with properties harveyi.