Pharmacovigilance in oncology: evaluation of current practice and future perspectives.

摘要: Rationale, aims and objectives Pharmacovigilance (PV), or drug safety monitoring, to improve patient through the detection management of drug-related adverse reactions. It is implemented both by spontaneous reporting reactions (ADRs) careful signals suggestive toxicity. PV an important clinical topic in practice pharmacotherapy, assuring maintenance a safe risk/benefit ratio throughout commercial life cycle drug. Methods We conducted structured literature search on PubMed, Scopus, Cinahl Cochrane Library. We also performed manual searches international databases ADR individual reports outline profile topic. Our goal was review key elements that affect monitoring cancer drugs their appropriate use, highlighting strengths weaknesses oncology. Results This paper provides understanding methodologies used current particularly therapy; focus upon ADRs health professionals patients; methods detect new risk/harm related medicines utilization. Conclusion To our knowledge, few articles importance post-marketing surveillance therapies. Structured data collection essential use this field which pharmacotherapy affected high incidence complications narrow benefit/risk ratio.