Pharmacogenetic risk for adverse reactions to irinotecan in the major ethnic populations of Singapore: regulatory evaluation by the health sciences authority.
作者： Cynthia Sung , Pui Ling Lee , Liesbet L. Tan , Dorothy S.L. Toh
DOI: 10.2165/11594440-000000000-00000
关键词:
摘要: Background: For genetic polymorphisms known to alter drug effect or safety, regulatory authorities can tap into population genomic databases and other sources of allele genotype distribution data make a more informed decision about the anticipated impact such variants on main ethnic groups in country’s population.
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