Embryonic neural transplants across a major histocompatibility barrier: survival and specificity of innervation.
作者： Walter C. Low , Peter R. Lewis , S. Terri Bunch
DOI: 10.1016/0006-8993(83)91028-4
关键词:
摘要: The ability of embryonic tissue to survive cross-transplantation between histologically incompatible rat strains was examined by transplanting septal neurons from Sprague Dawley fetuses adult Wistar rats (Ag-B6 Ag-B2 histocompatibility haplotype). Transplants were found without rejection over a period 3 months. Furthermore, the laminar pattern cholinergic innervation similar that homogenic transplants and intrinsic projections. These results suggest neural transplanted across major barriers are capable survival for extended periods time, in support concept privileged nature as source material cross-transplantation.
elsevier.com
sci-hub.se 参考文章(30)
P. R. Lewis, D. P. Knight, Staining Methods for Sectioned Material ,(1977)
Clyde F. Barker, R.E. Billingham, Immunologically Privileged Sites Advances in Immunology. ,vol. 25, pp. 1- 54 ,(1978) , 10.1016/S0065-2776(08)60930-X
Harry S. N. Greene, The induction of the Shope papilloma in transplants of embryonic rabbit skin. Cancer Research. ,vol. 13, pp. 58- 63 ,(1953)
Harry S. N. Greene, Wilhelm S. Albrink, The transplantation of tissues between zoological classes. Cancer Research. ,vol. 13, pp. 64- 68 ,(1953)
Niels Sunde And, Jens Zimmer, Transplantation of central nervous tissue. An introduction with results and implications. Acta Neurologica Scandinavica. ,vol. 63, pp. 323- 335 ,(2009) , 10.1111/J.1600-0404.1981.TB00786.X
Ulf Stenevi, Anders Bjo¨rklund, Niels-Aage Svendgaard, Transplantation of central and peripheral monoamine neurons to the adult rat brain: Techniques and conditions for survival Brain Research. ,vol. 114, pp. 1- 20 ,(1976) , 10.1016/0006-8993(76)91003-9
M. Perlow, W. Freed, B. Hoffer, A Seiger, L Olson, R. Wyatt, Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system Science. ,vol. 204, pp. 643- 647 ,(1979) , 10.1126/SCIENCE.571147
A. Björklund, S.B. Dunnett, U. Stenevi, M.E. Lewis, S.D. Iversen, Reinnervation of the denervated striatum by substantia nigra transplants: functional consequences as revealed by pharmacological and sensorimotor testing. Brain Research. ,vol. 199, pp. 307- 333 ,(1980) , 10.1016/0006-8993(80)90692-7
D Gash, J. Sladek, C. Sladek, Functional development of grafted vasopressin neurons Science. ,vol. 210, pp. 1367- 1369 ,(1980) , 10.1126/SCIENCE.7434031
Anders Bjo¨rklund, Menahem Segal, Ulf Stenevi, Functional reinnervation of rat hippocampus by locus coeruleus implants. Brain Research. ,vol. 170, pp. 409- 426 ,(1979) , 10.1016/0006-8993(79)90961-2