The stretch modulus of human cervical tissue in spontaneous, oxytocin-induced, and prostaglandin E2-induced labor

作者: John T. Conrad , Kent Ueland

DOI: 10.1016/0002-9378(79)90403-4

关键词:

摘要: Abstract A total of 62 strips cervical tissue from 28 patients at term were tested for stiffness (stretch modulus) by elongation and measuring the tension produced a given stretch. The stretch modulus was taken as slope linear regression curve derived portion stress-strain relationship. data obtained three patient categories: (1) 17 seven undergoing spontaneous labor, (2) 18 10 with labor induced PGE 2 , (3) 27 11 oxytocin. moduli oxytocin-induced similar. -induced significantly lower than those either or groups. These results show that when used induction term, has ability to tissue. This property prostaglandin may be useful therapeutically indicated in an unfavorable cervix.

参考文章(14)
A.I. Csapo, J.P. Sauvage, W.G. Wiest, The efficacy and acceptability of intravenously administered prostaglandin F2α as an abortifacient American Journal of Obstetrics and Gynecology. ,vol. 111, pp. 1059- 1063 ,(1971) , 10.1016/0002-9378(71)90104-9
J.F. Roux, M. Mofid, P.L. Moss, K.C. Dmytrus, Effect of elective induction of labor with prostaglandins F2α and E2 and oxytocin on uterine contraction and relaxation American Journal of Obstetrics and Gynecology. ,vol. 127, pp. 718- 722 ,(1977) , 10.1016/0002-9378(77)90245-9
John T. Conrad, Kent Ueland, Reduction of the stretch modulus of human cervical tissue by prostaglandin E2 American Journal of Obstetrics and Gynecology. ,vol. 126, pp. 218- 223 ,(1976) , 10.1016/0002-9378(76)90278-7
C.H. Hendricks, W.E. Brenner, L. Ekbladh, V. Brotanek, J.I. Fishburne, Efficacy and tolerance of intravenous prostaglandins F2α and E2 American Journal of Obstetrics and Gynecology. ,vol. 111, pp. 564- 579 ,(1971) , 10.1016/0002-9378(71)90473-X
Gerald G. Anderson, Induction of term labor with intravenous PGF2α: A review Prostaglandins. ,vol. 4, pp. 765- 774 ,(1973) , 10.1016/S0090-6980(73)80063-2
W.E. Benner, J.R. Dingfelder, L.G. Staurovsky, C.H. Hendricks, Vaginally administered PGF2α for cervical dilatation in nulliparas prior to suction curettage Prostaglandins. ,vol. 4, pp. 819- 836 ,(1973) , 10.1016/0090-6980(73)90117-2
Norman D Freid, Donald R Tredway, Daniel R Mishell, Termination of early pregnancy with prostaglandin E2 vaginal suppositories Contraception. ,vol. 8, pp. 255- 263 ,(1973) , 10.1016/0010-7824(73)90035-8
A. Johnson, D. Hyatt, J. Newton, L. Phillips, Experience with prostaglandin F2α (free acid) for the induction of labour Prostaglandins. ,vol. 7, pp. 487- 500 ,(1974) , 10.1016/0090-6980(74)90093-8