Cholinesterase inhibitors increase secretion of APPs in rat brain cortex.

作者: Francesca Mori , Chen-Ching Lai , Fabio Fusi , Ezio Giacobini

DOI: 10.1097/00001756-199503000-00012

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摘要: WE examined whether cholinesterase inhibitors (ChEI) could alter the release of amyloid precursor protein (APP) from superfused brain cortical slices rat. Three ChEI, both reversible and irreversible, were tested for their ability to enhance nonamyloidogenic soluble derivatives

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