Robust two-degree-of-freedom control: a simulation-based approach for adults population with T1D

摘要: Diabetes Mellitus (DM) is emerging as a global concern, affecting people from early ages to adulthood and positioning itself as one of the leading causes of mortality worldwide. The post-COVID-19 era has been characterized by notable progress in the domains of medicine, science, and engineering, creating a favorable atmosphere for the investigation of innovative solutions. The present manuscript aims to investigate the problem of glucose regulation in adults diagnosed with Type 1 Diabetes mellitus (T1D) using a two-degree-of-freedom robust controller technique. A physiological mathematical model involving individuals with T1D serves as the foundation for the proposed closed-loop technique. The control algorithm approach successfully maintains safe glycemic levels in a virtual population of 10 adults using a sophisticated, well-known physiological T1D simulator. We evaluated this with continuous 24-hour …