The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets

Kimberley El , Jonathan D Douros , Francis S Willard , Aaron Novikoff
Nature Metabolism 5 ( 6) 945 -954

29
2023
Spatiotemporal GLP-1 and GIP receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists.

Martin Klingenspor , Anja Zeigerer , Davide Calebiro , Davide Calebiro
Molecular metabolism 49 101181 -101181

4
2021
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling.

Diego Perez-Tilve , Martin Jastroch , Matthias H. Tschöp , Richard D. DiMarchi
Cell Metabolism 33 ( 4)

72
2021
POMC neuronal heterogeneity in energy balance and beyond: an integrated view.

Matthias H. Tschöp , Sabrina Diano , Giles S.H. Yeo , Lori M. Zeltser
Nature Metabolism 3 ( 3) 299 -308

53
2021
Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension

Tim Gruber , Chenchen Pan , Raian E Contreras , Tobias Wiedemann
Cell Metabolism 33 ( 6)

46
2021
Ghrelin and its potential in the treatment of eating/wasting disorders and cachexia

Timo D. Müller , Diego Perez-Tilve , Jenny Tong , Paul T. Pfluger
Journal of Cachexia, Sarcopenia and Muscle 1 ( 2) 159 -167

43
2010
Altered Lipid and Salt Taste Responsivity in Ghrelin and GOAT Null Mice

Huan Cai , Wei-na Cong , Caitlin M. Daimon , Rui Wang
PLOS ONE 8 ( 10)

34
2013
Insights into incretin-based therapies for treatment of diabetic dyslipidemia.

Kerstin Stemmer , Brian Finan , Richard D. DiMarchi , Matthias H. Tschöp
Advanced Drug Delivery Reviews 159 34 -53

18
2020
Functional identity of hypothalamic melanocortin neurons depends on Tbx3.

Carmelo Quarta , Alexandre Fisette , Yanjun Xu , Gustav Colldén
Nature Metabolism 1 ( 2) 222 -235

15
2019
Targeted pharmacological therapy restores β-cell function for diabetes remission.

Stephan Sachs , Aimée Bastidas-Ponce , Sophie Tritschler , Mostafa Bakhti
Nature Metabolism 2 ( 2) 192 -209

73
2020
Gastrointestinal signalling peptides in obesity

Ruben Nogueiras , Samantha J. Caton , Diego Perez-Tilve , Martin Bidlingmaier
Drug Discovery Today: Disease Mechanisms 3 ( 4) 463 -470

1
2006
Determination of thyroid hormones in mouse tissues by isotope-dilution microflow liquid chromatography–mass spectrometry method

Meri De Angelis , Florian Giesert , Brian Finan , Christoffer Clemmensen
Journal of Chromatography B 1033-1034 413 -420

22
2016
Consuming fructose-sweetened beverages increases body adiposity in mice

Hella Jürgens , Wiltrud Haass , Tamara R. Castañeda , Annette Schürmann
Obesity Research 13 ( 7) 1146 -1156

251
2005
Low-carbohydrate high-fat diets: regulation of energy balance and body weight regain in rats.

Samantha J. Caton , Bai Yinglong , Lukas Burget , Lothar J. Spangler
Obesity 17 ( 2) 283 -289

23
2009
Deficiency of glucose-dependent insulinotropic polypeptide receptor prevents ovariectomy-induced obesity in mice.

Frank Isken , Andreas F. H. Pfeiffer , Rubén Nogueiras , Martin A. Osterhoff
American Journal of Physiology-endocrinology and Metabolism 295 ( 2)

39
2008
Identification of GPR83 as the receptor for the neuroendocrine peptide PEN

Ivone Gomes , Erin N. Bobeck , Elyssa B. Margolis , Achla Gupta
Science Signaling 9 ( 425) 43

36
2016
Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency.

Sonja C. Schriever , Annemarie Zimprich , Katrin Pfuhlmann , Peter Baumann
Neuroscience 357 241 -254

20
2017
Action profile of the antiobesity drug candidate oleoyl-estrone in rats.

Sabine Strassburg , Paul T. Pfluger , Nilika Chaudhary , Patrick Tso
Obesity 18 ( 12) 2260 -2267

5
2010
Hypothalamic Injury: Fish Oil to the Rescue!

Cristina García-Cáceres , Matthias H. Tschöp
Diabetes 65 ( 3) 551 -553

2
2016