Discovery of GDC-0077 (inavolisib), a highly selective inhibitor and degrader of mutant PI3Kα
Emily J Hanan , Marie-Gabrielle Braun , Robert A Heald , Calum MacLeod
Journal of Medicinal Chemistry 65 ( 24) 16589 -16621
26
2022
Constitutive protein degradation induces acute cell death via proteolysis products
Si-Han Chen , Sumit Prakash , Elizabeth Helgason , Caroline L Gilchrist
bioRxiv 2023.02. 06.527237 -2023.02. 06.527237
1
2023
Abstract# 3816: Insights into the activation mechanism of EGF receptor from the structure of the inactive kinase domain dimer
Natalia Jura , Nicholas Endres , Kate Engel , Sebastian Deindl
Cancer Research 69 ( 9_Supplement) 3816 -3816
2009