Catalytic Control in the EGF Receptor and Its Connection to General Kinase Regulatory Mechanisms
Natalia Jura , Xuewu Zhang , Nicholas F. Endres , Markus A. Seeliger
Molecular Cell 42 ( 1) 9 -22
227
2011
Architecture and Membrane Interactions of the EGF Receptor
Anton Arkhipov , Yibing Shan , Rahul Das , Nicholas F. Endres
Cell 152 ( 3) 557 -569
328
2013
Conformational Coupling across the Plasma Membrane in Activation of the EGF Receptor.
Nicholas F. Endres , Rahul Das , Adam W. Smith , Anton Arkhipov
Cell 152 ( 3) 543 -556
325
2013
Regulation of the catalytic activity of the EGF receptor
Nicholas F Endres , Kate Engel , Rahul Das , Erika Kovacs
Current Opinion in Structural Biology 21 ( 6) 777 -784
81
2011
Anisotropic Dynamics of the JE-2147− HIV Protease Complex: Drug Resistance and Thermodynamic Binding Mode Examined in a 1.09 Å Structure
K Kinkead Reiling , Nicholas F Endres , Deborah S Dauber , Charles S Craik
Biochemistry 41 ( 14) 4582 -4594
67
2002
Autoinhibition Regulates the Motility of the C. elegans Intraflagellar Transport Motor OSM-3
Miki Imanishi , Nicholas F Endres , Arne Gennerich , Ronald D Vale
The Journal of Cell Biology 174 ( 7) 931 -937
117
2006
High-throughput kinetic characterization of irreversible covalent inhibitors of KRASG12C by intact protein MS and targeted MRM
Ke Sherry Li , John G Quinn , Matthew J Saabye , Jesus F Salcido Guerrero
Analytical Chemistry 94 ( 2) 1230 -1239
12
2022
Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors
Christian Nilewski , Sharada Labadie , Binqing Wei , Sushant Malhotra
ACS Medicinal Chemistry Letters 15 ( 1) 21 -28
1
2023
High-Throughput Kinetic Characterization of Irreversible Covalent Inhibitors of KRASᴳ¹²C by Intact Protein MS and Targeted MRM
Ke Sherry Li , John G Quinn , Matthew J Saabye , Jesus F Salcido Guerrero
2022
Selective degradation of mutant PIK3CA promotes increased mutant specificity in a subset of PI3K ATP-competitive inhibitors
Lan Nguyen , Kyle Edgar , Kyung Song , Stephen Schmidt
MOLECULAR CANCER RESEARCH 18 ( 10) 43 -43
2020
Examining kinesin motor family diversity: A mechanistic study of Ncd and OSM-3 motor proteins
Nicholas F Endres
University of California, San Francisco
2006
Supplemental Data Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane Segment
Natalia Jura , Nicholas F Endres , Kate Engel , Sebastian Deindl
The next issue of this journal
Niall S Kenneth , Robert J White , Lauren L Campbell Marotta , Kornelia Polyak
The next issue of this journal
Andres Leschziner , Sheena D’Arcy , Karolin Luger , Mark Bycroft
Dynamic Organization of Myristoylated Src in the Live Cell Plasma Membrane.
Adam W. Smith , Hector H. Huang , Nicholas F. Endres , Christopher Rhodes
Journal of Physical Chemistry B 120 ( 5) 867 -876
10
2016
Abstract PR03: Selective degradation of mutant PIK3CA promotes increased mutant specificity in a subset of PI3K ATP-competitive inhibitors
Lan Nguyen , Kyle Edgar , Kyung Song , Stephen Schmidt
Molecular Cancer Research 18
2020
A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd
Nicholas F. Endres , Craig Yoshioka , Ronald A. Milligan , Ronald D. Vale
Nature 439 ( 7078) 875 -878
92
2006
Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane Segment
Natalia Jura , Nicholas F. Endres , Kate Engel , Sebastian Deindl
Cell 137 ( 7) 1293 -1307
436
2009
Emerging concepts in the regulation of the EGF receptor and other receptor tyrosine kinases
Nicholas F. Endres , Tiago Barros , Aaron J. Cantor , John Kuriyan
Trends in Biochemical Sciences 39 ( 10) 437 -446
50
2014
RTK-dependent inducible degradation of mutant PI3Kα drives GDC-0077 (Inavolisib) efficacy
Kyung W Song , Kyle A Edgar , Emily J Hanan , Marc Hafner
Cancer discovery 12 ( 1) 204 -219
43
2022