引用次数
引用: 62,810
H-指数: 116
I10-指数 : 220
出版物: 385
Structure of a Sliding Clamp on DNA
Roxana E. Georgescu , Seung-Sup Kim , Olga Yurieva , John Kuriyan
Cell 132 ( 1) 43 -54
182
2008
Oncogenic mutations counteract intrinsic disorder in the EGFR kinase and promote receptor dimerization
Yibing Shan , Michael P. Eastwood , Xuewu Zhang , Eric T. Kim
Cell 149 ( 4) 860 -870
231
2012
The Mechanism of Linkage-Specific Ubiquitin Chain Elongation by a Single-Subunit E2
Katherine E. Wickliffe , Sonja Lorenz , David E. Wemmer , John Kuriyan
Cell 144 ( 5) 769 -781
217
2011
Comparative Analysis of Mutant Tyrosine Kinase Chemical Rescue
Kathryn E. Muratore , Markus A. Seeliger , Zhihong Wang , Dina Fomina
Biochemistry 48 ( 15) 3378 -3386
14
2009
Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia
Catherine C. Smith , Qi Wang , Chen-Shan Chin , Sara Salerno
Nature 485 ( 7397) 260 -263
780
2012
Inhibition of BCR/ABL-T315I by Dismantling the Hydrophobic Spine.
Mohammad Azam , Markus Seeliger , John T Powers , Nathanael Gray
Blood 112 ( 11) 2129 -2129
2008
Equally potent inhibition of c-Src and Abl by compounds that recognize inactive kinase conformations
Markus A. Seeliger , Pratistha Ranjitkar , Corynn Kasap , Yibing Shan
Cancer Research 69 ( 6) 2384 -2392
168
2009
MODULAR PEPTIDE RECOGNITION DOMAINS IN EUKARYOTIC SIGNALING
John Kuriyan , David Cowburn
Annual Review of Biophysics and Biomolecular Structure 26 ( 1) 259 -288
492
1997
A highly efficient peptide substrate for EGFR activates the kinase by inducing aggregation
Kate Engel , Tomoaki Sasaki , Qi Wang , John Kuriyan
Biochemical Journal 453 ( 3) 337 -344
5
2013
The Tyrosine Kinase Csk Dimerizes through Its SH3 Domain
Nicholas M. Levinson , Patrick R. Visperas , John Kuriyan
PLoS ONE 4 ( 11) e7683
20
2009
Crystal Structure of the Kinase Domain of ABL in Complex with a Potent Rationally-Designed Derivative of the PP1 Inhibitor, AB129
M. Nidanie Henderson , Kathryn E. Malecek , Deborah L. Makino , Xiaoxian X. Cao
Biophysical Journal 102 ( 3) 61a
2012
Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
Neil P. Shah , John M. Nicoll , Bhushan Nagar , Mercedes E. Gorre
Cancer Cell 2 ( 2) 117 -125
1,515
2002
Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen
Neel H Shah , Mark Löbel , Arthur Weiss , John Kuriyan
eLife 7
20
2018
Ras activation by SOS: Allosteric regulation by altered fluctuation dynamics
Lars Iversen , Hsiung-Lin Tu , Wan-Chen Lin , Sune M. Christensen
Science 345 ( 6192) 50 -54
84
2014
The structure, regulation, and function of ZAP-70
Byron B. Au-Yeung , Sebastian Deindl , Lih-Yun Hsu , Emil H. Palacios
Immunological Reviews 228 ( 1) 41 -57
242
2009
Mapping the interaction of DNA with the Escherichia coli DNA polymerase clamp loader complex
Eric R Goedken , Steven L Kazmirski , Gregory D Bowman , Mike O'Donnell
Nature Structural & Molecular Biology 12 ( 2) 183 -190
40
2005
The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases.
Neel H. Shah , Jeanine F. Amacher , Laura M. Nocka , John Kuriyan
Critical Reviews in Biochemistry and Molecular Biology 53 ( 5) 535 -563
29
2018
Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT.
Wan-Lin Lo , Neel H Shah , Nagib Ahsan , Veronika Horkova
Nature Immunology 19 ( 7) 733 -741
48
2018
Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination.
Wan-Lin Lo , Neel H Shah , Sara A Rubin , Weiguo Zhang
Nature Immunology 20 ( 11) 1481 -1493
20
2019