Lipoxygenases: Potential Therapeutic Target in Atherosclerosis
C.D. Funk , L. Zhao
CRC Press 207 -218
3
2005
Cloning of a human "epidermal-type" 12-lipoxygenase-related gene and chromosomal localization to 17p13.
D. Sun , S.H. Elsea , P.I. Patel , C.D. Funk
Cytogenetic and Genome Research 81 ( 1) 79 -82
27
1998
Fibronectin-Induced Cell Spreading and Down-Regulation of 12-Lipoxygenase Expression in Megakaryocytic DAMI Cells
W. Kuchinke , C.D. Funk
Biochemical and Biophysical Research Communications 204 ( 2) 606 -612
7
1994
Mice deficient for 5-lipoxygenase, but not leukocyte-type 12-lipoxygenase, display altered immune responses during infection with Schistosoma mansoni
W.E. Secor , M.R. Powell , J. Morgan , T.A. Wynn
Prostaglandins & Other Lipid Mediators 56 ( 5) 291 -304
19
1998
Eicosanoid forming enzyme mRNA in human tissues. Analysis by quantitative polymerase chain reaction.
C.D. Funk , G.A. FitzGerald
Journal of Biological Chemistry 266 ( 19) 12508 -12513
69
1991
Targeted disruption of the murine decay-accelerating factor (DAF) gene: Studies of erythrocytes reveal activity of DAF in regulating both autologous and heterologous complement activation
X. Sun , C.D. Funk , C. Deng , A. Sahu
Molecular Immunology 35 372
1998
EXAMINATION OF THE 5-LIPOXYGENASE/LEUKOTRIENE PATHWAY IN ADVANCED ATHEROSCLEROTIC LESION AND ABDOMINAL AORTIC ANEURYSM DEVELOPMENT IN 5-LIPOXYGENASE/APOE DEFICIENT MICE
R.Y. Cao , C.D. Funk
Atherosclerosis Supplements 9 ( 1) 1
2008
Chromosomal localization of the human prostanoid receptor gene family.
A.M.V. Duncan , L.L. Anderson , C.D. Funk , M. Abramovitz
Genomics 25 ( 3) 740 -742
27
1995
134 DECREASED HEPATIC MACROPHAGE INFILTRATION, INSULIN RESISTANCE AND TNFa-INDUCED HEPATOCYTE DAMAGE IN APOE/5-LIPOXYGENASE DOUBLE KNOCKOUT MICE
M. Martínez-Clemente , N. Ferré , M. López-Parra , R. Horrillo
Journal of Hepatology 50 ( 50)
2009
cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases.
X.S. Chen , U. Kurre , N.A. Jenkins , N.G. Copeland
Journal of Biological Chemistry 269 ( 19) 13979 -13987
187
1994
064 Cysteinyl leukotriene 2 receptor-specific antagonist attenuates inflammation response-mediated myocardial ischemia/reperfusion injury
N.C. Ni , D. Yan , A.R. Barajas Espinosa , L.L. Ballantyne
Canadian Journal of Cardiology 27 ( 5)
2011
Expression of porcine leukocyte 12-lipoxygenase in a baculovirus/insect cell system and its characterization.
R.G. Reddy , T. Yoshimoto , S. Yamamoto , C.D. Funk
Archives of Biochemistry and Biophysics 312 ( 1) 219 -226
24
1994
Leukotriene A4, conversion to leukotriene B4 in human T-cell lines.
Fu Ji Yi , J.F. Medina , C.D. Funk , A. Wetterholm
Prostaglandins 36 ( 2) 241 -248
24
1988
Is There a Role for the Macrophage 5-Lipoxygenase Pathway in Aortic Aneurysm Development in Apolipoprotein E-Deficient Mice?
C. D FUNK , R. Y. CAO , L. ZHAO , A. J.R HABENICHT
Annals of the New York Academy of Sciences 1085 ( 1) 151 -160
10
2006
5-Lipoxygenase and leukotrienes. Transgenic mouse and nuclear targeting studies.
COLIN D. FUNK , XIN-SHENG CHEN
American Journal of Respiratory and Critical Care Medicine 161 ( 2)
34
2000
Directed vascular expression of the thromboxane A (2) receptor.
B Rocca , AL Loeb , V Eng , R Vezza
JOURNAL OF INVESTIGATIVE MEDICINE 46 ( 3) 230A -230A
1998
Role of 5-lipoxygenase in mouse models of atherosclerosis
L Zhao , JJ Fan , CD Funk ,
Circulation 108 ( 17) 196 -196
1
2003
The 5-lipoxygenase pathway in atherosclerosis and aortic aneurysm pathogenesis
L Zhao , MP Moos , R Grabner , F Pedrono
CIRCULATION 110 ( 17) 178 -178
2004
Low-dose aspirin reduces atherogenesis and increases plaque stability in LDL-receptor deficient mice
T Cyrus , S Song , L Zhao , CD Funk
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 22 ( 5) A4 -A4
2002
Pro-atherogenic role of 12/15-lipoxygenase in two mouse models of atherosclerosis
L Zhao , T Cyrus , CD Funk
CIRCULATION 104 ( 17) 64 -+
2001