Vedagopuram Sreekanth
机构: Research Scientist: Broad Institute of MIT and Harvard
主页: researchgate.net
每年引用次数
引用次数
引用: 639
H-指数: 16
I10-指数 : 21
出版物: 40
A 3D culture platform enables development of zinc-binding prodrugs for targeted proliferation of β cells
Angela Zhou , Jun Xu , Vedagopuram Sreekanth , Jamie L. Y. Wu
Science Advances 6 ( 47)
18
2020
Recent Advances in Engineering of Lipid Drug Conjugates for Cancer Therapy.
Vedagopuram Sreekanth , Avinash Bajaj
ACS Biomaterials Science & Engineering 5 ( 9) 4148 -4166
9
2019
Fluorescence (Fluidity/Hydration) and Calorimetric Studies of Interactions of Bile Acid–Drug Conjugates with Model Membranes
Vedagopuram Sreekanth , Avinash Bajaj
Journal of Physical Chemistry B 117 ( 7) 2123 -2133
11
2013
Design, regioselective synthesis and cytotoxic evaluation of 2-aminoimidazole-quinoline hybrids against cancer and primary endothelial cells.
Kuldeep Singh , Vikas Verma , Kavita Yadav , Vedagopuram Sreekanth
European Journal of Medicinal Chemistry 87 150 -158
19
2014
Design, Synthesis, and Mechanistic Investigations of Bile Acid–Tamoxifen Conjugates for Breast Cancer Therapy
Vedagopuram Sreekanth , Sandhya Bansal , Rajender K. Motiani , Somanath Kundu
Bioconjugate Chemistry 24 ( 9) 1468 -1484
29
2013
Nature of the charged headgroup determines the fusogenic potential and membrane properties of lithocholic acid phospholipids.
Priyanshu Bhargava , Manish Singh , Vedagopuram Sreekanth , Avinash Bajaj
Journal of Physical Chemistry B 118 ( 31) 9341 -9348
10
2014
Molecular Self-Assembly of Bile Acid-Phospholipids Controls the Delivery of Doxorubicin and Mice Survivability
Vedagopuram Sreekanth , Nihal Medatwal , Sanjay Pal , Sandeep Kumar
Molecular Pharmaceutics 14 ( 8) 2649 -2659
5
2017
Bile Acid Tethered Docetaxel-Based Nanomicelles Mitigate Tumor Progression through Epigenetic Changes.
Arnab Mukhopadhyay , Sagar Sengupta , Ujjaini Dasgupta , Avinash Bajaj
Angewandte Chemie 60 ( 10) 5394 -5399
2021
A conjugation platform for CRISPR-Cas9 allows efficient β-cell engineering
Donghyun Lim , Vedagopuram Sreekanth , Kurt J. Cox , Benjamin K. Law
bioRxiv 732354
2019
Tethering of Chemotherapeutic Drug/Imaging Agent to Bile Acid-Phospholipid Increases the Efficacy and Bioavailability with Reduced Hepatotoxicity
Vedagopuram Sreekanth , Nihal Medatwal , Sandeep Kumar , Sanjay Pal
Bioconjugate Chemistry 28 ( 12) 2942 -2953
7
2017
Chemogenetic System Demonstrates That Cas9 Longevity Impacts Genome Editing Outcomes.
Vedagopuram Sreekanth , Qingxuan Zhou , Praveen Kokkonda , Heysol C. Bermudez-Cabrera
ACS central science 6 ( 12) 2228 -2237
1
2020
Number of free hydroxyl groups on bile acid phospholipids determines the fluidity and hydration of model membranes.
Vedagopuram Sreekanth , Avinash Bajaj
Journal of Physical Chemistry B 117 ( 40) 12135 -12144
11
2013
Engineering designer beta cells with a CRISPR-Cas9 conjugation platform.
Donghyun Lim , Vedagopuram Sreekanth , Kurt J. Cox , Benjamin K. Law
Nature Communications 11 ( 1) 4043
30
2020
Synthesis, structure–activity relationship, and mechanistic investigation of lithocholic acid amphiphiles for colon cancer therapy
Manish Singh , Sandhya Bansal , Somanath Kundu , Priyanshu Bhargava
MedChemComm 6 ( 1) 192 -201
27
2015
Bile acid amphiphiles with tunable head groups as highly selective antitubercular agents
Sandhya Bansal , Manish Singh , Saqib Kidwai , Priyanshu Bhargava
MedChemComm 5 ( 11) 1761 -1768
31
2014
Nature of the charged head group dictates the anticancer potential of lithocholic acid-tamoxifen conjugates for breast cancer therapy
Kavita Yadav , Priyanshu Bhargava , Sandhya Bansal , Manish Singh
MedChemComm 6 ( 5) 778 -787
5
2015
Injectable small molecule hydrogel as a potential nanocarrier for localized and sustained in vivo delivery of doxorubicin
Manish Singh , Somanath Kundu , Amarendar Reddy M , Vedagopuram Sreekanth
Nanoscale 6 ( 21) 12849 -12855
54
2014
A molecular glue approach to control the half-life of CRISPR-based technologies
Vedagopuram Sreekanth , Max Jan , Kevin T Zhao , Donghyun Lim
bioRxiv
3
2023
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity
Nicolas Wieder , Juliana Coraor Fried , Choah Kim , Eriene-Heidi Sidhom
Cell metabolism 35 ( 5) 887 -905. e11
7
2023
Photoswitchable Molecular Glues Enable Optical Control of Transcription Factor Degradation
Christopher J Arp , Martin Reynders , Vedagopuram Sreekanth , Praveen Kokkonda
bioRxiv
2023
Avinash Bajaj, PhD Amit Choudhary Sagar Sengupta Donghyun Lim Rajender Motiani; DVM, PhD Jeffrey M. Karp David R. Liu Basudeb Maji Benjamin L. Ebert Max Jan Aasheesh Srivastava Shantanu Chowdhury Richard I Sherwood Dr.Vinod Kumar James A. Walker George Church Luca Pinello Martin Kampmann Dirk Trauner Ramandeep Singh