Tissue distribution and immunoreactivity of heme-regulated eIF-2 alpha kinase determined by monoclonal antibodies.
Jayanta K. Pal , Jane Jane Chen , Irving M. London
Biochemistry 30 ( 9) 2555 -2562
48
1991
Requirement of activating transcription factor 5 for murine fetal liver erythropoiesis.
Shuping Zhang , Jane‐Jane Chen
British Journal of Haematology 188 ( 4) 582 -585
1
2020
The Role of the 90‐kDa Heat‐Shock Protein and its Associated Cohorts in Stabilizing the Heme‐Regulated Eif‐24Al Kinase in Reticulocyte Lysates during Heat Stress
Zuoyu Xu , Jayanta K Pal , Vanitha Thulasiraman , Hejin P Hahn
European journal of biochemistry 246 ( 2) 461 -470
59
1997
Heme‐regulated eIF2α kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency
An‐Ping Han , Channing Yu , Linrong Lu , Yuko Fujiwara
The EMBO journal
481
2001
The N‐terminal region of the heme‐regulated eIF2α kinase is an autonomous heme binding domain
Sheri Uma , Robert L Matts , Yanwen Guo , Steven White
European Journal of Biochemistry 267 ( 2) 498 -506
55
2000
Evidence that Hsc70 negatively modulates the activation of the heme‐regulated eIF‐2α kinase in rabbit reticulocyte lysate
Vanitha Thulasiraman , Zuoyu Xu , Sheri Uma , Yan Gu
European journal of biochemistry 255 ( 3) 552 -562
52
1998
Heme‐regulated eIF‐2α kinase purifies as a hemoprotein
Peter Joseph Chefalo , Jihyun Oh , Maryam Rafie‐Kolpin , Beki Kan
European journal of biochemistry 258 ( 2) 820 -830
108
1998
Translational control by heme-regulated eIF2α kinase during erythropoiesis
Jane-Jane Chen
Current Opinion in Hematology 21 ( 3) 172 -178
57
2014
The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling.
Mena Abdel-Nour , Leticia A. M. Carneiro , Jeffrey Downey , Jessica Tsalikis
Science 365 ( 6448)
33
2019
Hsp90 Is Obligatory for the Heme-regulated eIF-2α Kinase to Acquire and Maintain an Activable Conformation
Sheri Uma , Steven D. Hartson , Jane-Jane Chen , Robert L. Matts
Journal of Biological Chemistry 272 ( 17) 11648 -11656
77
1997
Oxidative Stress Signaling Pathway of Heme Regulated eIF2α Kinase in mitigating the Severity of β-Thalassemia
Rajasekhar NVS Suragani , Sijin Liu , Wanting Zhao , Jane-Jane Chen
Blood 112 ( 11) 127 -127
5
2008
Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies
Jane-Jane Chen , Shuping Zhang
Blood 134 ( 20) 1697 -1707
17
2019
Stressing HbF synthesis: role of translation?
Jane-Jane Chen , Susan Perrine
Blood 122 ( 4) 467 -468
5
2013
HRI coordinates translation by eIF2αP and mTORC1 to mitigate ineffective erythropoiesis in mice during iron deficiency
Shuping Zhang , Alejandra Macias-Garcia , Jason Velazquez , Elena Paltrinieri
Blood 131 ( 4) 450 -461
35
2018
Regulation of globin-heme balance in Diamond-Blackfan anemia by HSP70/GATA1.
Sarah Rio , Marc Gastou , Narjesse Karboul , Raphaёl Derman
Blood 133 ( 12) 1358 -1370
11
2019
HRI coordinates translation necessary for protein homeostasis and mitochondrial function in erythropoiesis
Shuping Zhang , Alejandra Macias-Garcia , Jacob C Ulirsch , Jason Velazquez
eLife 8
21
2019
Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis
Rajasekhar N. V. S. Suragani , Roshini S. Zachariah , Jason G. Velazquez , Sijin Liu
Blood 119 ( 22) 5276 -5284
94
2012
Microdosimetric and Biological Effects of Photon Irradiation at Different Energies in Bone Marrow
Matthew D. Belley , Kathleen A. Ashcraft , Chen-Ting Lee , Milton R. Cornwall-Brady
Radiation Research 184 ( 4) 378 -391
6
2015
Bitopertin, a selective oral GLYT1 inhibitor, improves anemia in a mouse model of β-thalassemia
Alessandro Matte , Enrica Federti , Michael Winter , Annette Koerner
JCI insight 4 ( 22) 1 -16
16
2019
HRI stress signaling and HbF production.
Jane-Jane Chen
Blood 135 ( 24) 2113 -2114
2020