Hypermethylation is a key feature of the transition of multiple myeloma to plasma cell leukemia
Brian A Walker , Christopher P Wardell , Kevin D Boyd , Emma M. Smith
Blood 116 ( 21) 535 -535
2
2010
Defining Myeloma Patients at High Risk of Developing Bone Disease While on Bisphosphonate Treatment
Ping Wu , Brian A Walker , Kevin D Boyd , Christopher P Wardell
Blood 116 ( 21) 782 -782
3
2010
Genetic Variations Associated with Overall and Progression-Free Survival in Multiple Myeloma Patients Treated with Thalidomide Combinations
David C Johnson , Walter M Gregory , Nicholas J Dickens , Brian A Walker
Blood 114 ( 22) 426 -426
2
2009
Gene Expression Profiling Classifies Splenic Marginal Zone Lymphoma and Hairy Cell Leukemia-Variant as Related Diseases That Are Distinct From Typical Hairy Cell Leukemia.
Sarah L Hockley , Alison Morilla , Andrew Wotherspoon , Brian A Walker
Blood 114 ( 22) 3467 -3467
2009
Exome Sequencing of the t(4;14) and t(11;14) Translocation Specific Subgroups of MM
Christopher P Wardell , Brian A Walker , David Johnson , Iwanka Kozarewa
Blood 118 ( 21) 1817 -1817
2011
A Novel Mouse Model of Multiple Myeloma Representative of Human Disease and Its Use in Preclinical Therapeutic Assessment
Rosemary A Fryer , Timothy J Graham , Emma M Smith , Brian A Walker
Blood 118 ( 21) 2907 -2907
2011
Whole Genome Sequencing Illuminates the Genetic and Biological Features Underlying the Transition of SMM to MM
Brian A Walker , Christopher P Wardell , Lucía López-Corral , Sean Humphray
Blood 118 ( 21) 296 -296
1
2011
Single-Cell Genetic Analysis Reveals The Genetic Composition Of Founder Clones, Phylogenetic Patterns Of Branching and Parallel Evolution, and Clonal Fluctuations Following Patient Treatment In Multiple Myeloma
Lorenzo Melchor , Annamaria Brioli , Christopher P Wardell , Alexander Murison
Blood 122 ( 21) 398 -398
1
2013
MYC Translocations In Multiple Myeloma Involve Recruitment Of Enhancer Elements Resulting In Over-Expression and Decreased Overall Survival
Brian A Walker , Christopher P Wardell , Dil Begum , Nasrin Dahir
Blood 122 ( 21) 274 -274
2013
Exome Sequencing To Define A Genetic Signature Of Plasma Cells In Systemic AL Amyloidosis
Brian A Walker , Dorota Rowczienio , Eileen M Boyle , Christopher P Wardell
Blood 122 ( 21) 3098 -3098
4
2013
A Rapid and Robust Molecular Diagnostic Approach For Multiple Myeloma – Results From a Large Trial Cohort
Martin F. Kaiser , Dil Begum , Paula Proszek , Nasrin Dahir
Blood 122 ( 21) 3097 -3097
2013
FOrMAT: Feasibility of a molecular characterization approach to treatment of patients (pts) with advanced gastrointestinal (GI) tumors
Sing Yu Moorcraft , David Gonzalez de Castro , David Cunningham , Brian A Walker
Journal of Clinical Oncology 33
2015
Concurrent Amplification of MYC and 1q21 in Multiple Myeloma: Focal and Segmental Jumping Translocations of MYC
Jeffery Sawyer , Erming Tian , Brian A Walker , Niels Weinhold
Blood 128 ( 22) 3266 -3266
1
2016
Multiple Myeloma with a Deletion of Chromosome 17p: TP53 Mutations Are Highly Prevalent and Negatively Affect Prognosis
Davine Hofste op Bruinink , Hoogenboezem Remco , Mathijs A. Sanders , Christopher P Wardell
Blood 128 ( 22) 3271 -3271
2016
Extensive Regional Intra-Clonal Heterogeneity in Multiple Myeloma - Implications for Diagnostics, Risk Stratification and Targeted Treatment
Niels Weinhold , Shweta S. Chavan , Leo Rasche , Owen W Stephens
Blood 128 ( 22) 3278 -3278
1
2016
Inhibition of the Epigenetic Modifier EZH2 Upregulates Cell Cycle Control Genes to Inhibit Myeloma Cell Growth and Overcome High-Risk Disease Features
Charlotte Pawlyn , Michael Bright , Amy Buros , Caleb K. Stein
Blood 128 ( 22) 3289 -3289
2
2016
The Impact of Maintenance Lenalidomide on the Mutational Status of the Myeloma Clone at Relapse in the NCRI Myeloma XI Trial for Newly Diagnosed Multiple Myeloma Patients (NDMM)
John R Jones , Niels Weinhold , Shweta S. Chavan , Charlotte Pawlyn
Blood 128 ( 22) 4412 -4412
2
2016
The Clinical Impact of Macrofocal Disease in Multiple Myeloma Differs Between Presentation and Relapse
Leo Rasche , Amy Buros , Niels Weinhold , Caleb K. Stein
Blood 128 ( 22) 4431 -4431
3
2016
The Mutational and Signaling Landscape of Multiple Myeloma Varies Dependent upon Translocation Cyclin D (TC) Subgroup
Caleb K. Stein , Charlotte Pawlyn , Shweta S. Chavan , Niels Weinhold
Blood 128 ( 22) 4441 -4441
1
2016
The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.
Niels Weinhold , David C Johnson , Daniel Chubb , Bowang Chen
Nature Genetics 45 ( 5) 522 -525
69
2013