Mellinghoff Ingo
机构: Memorial Sloan Kettering Cancer Center
每年引用次数
引用次数
引用: 35,177
H-指数: 75
I10-指数 : 150
出版物: 346
Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death
Nicholas A Graham , Martik Tahmasian , Bitika Kohli , Evangelia Komisopoulou
Molecular Systems Biology 8 ( 1) 589 -589
204
2012
Inferring loss-of-heterozygosity from unpaired tumors using high-density oligonucleotide SNP arrays.
Rameen Beroukhim , Ming Lin , Yuhyun Park , Ke Hao
PLOS Computational Biology 2 ( 5) 323 -332
157
2006
TORward AKTually useful mouse models
Ingo K Mellinghoff , Charles L Sawyers
Nature Medicine 10 ( 6) 579 -580
38
2004
The emergence of resistance to targeted cancer therapeutics.
Ingo K Mellinghoff , Charles L Sawyers
Pharmacogenomics 3 ( 5) 603 -623
22
2002
Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.
Jeffrey C Lee , Igor Vivanco , Rameen Beroukhim , Julie H. Y Huang
PLOS Medicine 3 ( 12) 2264 -2273
382
2006
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation
Luc G T Morris , Andrew M Kaufman , Yongxing Gong , Deepa Ramaswami
Nature Genetics 45 ( 3) 253 -261
392
2013
ACTR-46. AG-120, A FIRST-IN-class MUTANT IDH1 INHIBITOR IN PATIENTS WITH RECURRENT OR PROGRESSIVE IDH1 MUTANT GLIOMA: UPDATED RESULTS FROM THE PHASE 1 NON-ENHANCING GLIOMA POPULATION
Mehdi Touat , Elizabeth Maher , Macarena De La Fuente , Timothy F Cloughesy
Neuro-oncology 19
22
2017
NIMG-53. POST-SURGICAL, RESIDUAL ENHANCING TUMOR VOLUME IS PROGNOSTIC FOR OVERALL SURVIVAL IN NEWLY DIAGNOSED GLIOBLASTOMA: EVIDENCE FROM 1,458 PATIENTS POOLED FROM INTERNATIONAL TRIALS, SINGLE INSTITUTION DATABASES, AND MULTICENTER CONSORTIUMS
Benjamin Ellingson , Lauren Abrey , Sarah Nelson , Josep Garcia
Neuro-oncology 19
2017
Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma
Tim F Cloughesy , Koji Yoshimoto , Phioanh Nghiemphu , Kevin Brown
PLOS Medicine 5 ( 1) 139 -151
651
2008
Glioblastoma and other primary brain malignancies in adults: a review
Lauren R Schaff , Ingo K Mellinghoff
Jama 329 ( 7) 574 -587
2023
Isocitrate dehydrogenase (IDH) mutant gliomas: A Society for Neuro-Oncology (SNO) consensus review on diagnosis, management, and future directions
Julie J Miller , L Nicolas Gonzalez Castro , Samuel McBrayer , Michael Weller
Neuro-oncology 25 ( 1) 4 -25
4
2023
GCN2 kinase activation by ATP-competitive kinase inhibitors
Colin P Tang , Owen Clark , John R Ferrarone , Carl Campos
Nature chemical biology 18 ( 2) 207 -215
8
2022
Vorasidenib and ivosidenib in IDH1-mutant low-grade glioma: a randomized, perioperative phase 1 trial
Ingo K Mellinghoff , Min Lu , Patrick Y Wen , Jennie W Taylor
Nature Medicine 29 ( 3) 615 -622
2023
A phase 1, open-label, perioperative study of ivosidenib (AG-120) and vorasidenib (AG-881) in recurrent, IDH1-mutant, low-grade glioma: updated results
Ingo K Mellinghoff , Timothy F Cloughesy , Patrick Y Wen , Jennie W Taylor
Neuro-oncol 21 ( Suppl 6) vi28 -vi29
6
2019
INDIGO: A global, randomized, double-blind, phase III study of vorasidenib (VOR; AG-881) vs placebo in patients with residual or recurrent grade II glioma with an isocitrate dehydrogenase 1/2 (IDH1/2) mutation
Ingo K Mellinghoff , Martin J van den Bent , Jennifer L Clarke , Elizabeth A Maher
Screening 5 C19D1
IDH Mutations Offer Hope as a Prognostic Indicator and Treatable Target in Gliomas
Ingo K Mellinghoff
Smpte Journal
Next-generation sequencing of cerebrospinal fluid for clinical molecular diagnostics in pediatric, adolescent and young adult brain tumor patients
Alexandra M Miller , Luca Szalontay , Nancy Bouvier , Katherine Hill
Neuro-oncology 24 ( 10) 1763 -1772
13
2022
Glioblastoma mutational profiles drive cancer cell signaling and immune evasion
Maryam Pourmaleki , Brian D Greenstein , Caitlin J Jones , Subhiksha Nandakumar
Cancer Research 84 ( 6_Supplement) 3875 -3875
2024
Corrigendum: High-throughput oncogene mutation profiling in human cancer
Roman K Thomas , Alissa C Baker , Ralph M DeBiasi , Wendy Winckler
Nature genetics 39 ( 4) 567 -568
8
2007
Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma
Macarena I de la Fuente , Robert J Young , Jennifer Rubel , Marc Rosenblum
Neuro-oncology 18 ( 2) 283 -290
192
2015