Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles

Emma L Clayton , Nancy Sue , Karen J Smillie , Timothy O'Leary
Nature Neuroscience 13 ( 7) 845 -851

115
2010
Suppression of the intrinsic apoptosis pathway by synaptic activity

Frédéric Léveillé , Sofia Papadia , Michael Fricker , Karen FS Bell
Journal of Neuroscience 30 ( 7) 2623 -2635

168
2010
GluN2A Haploinsufficiency: a Novel Pre‐Clinical Model of Epilepsy

David J Wyllie , Sam A Booker , Farhana Yasmin , Grant Marshall
The FASEB Journal 32 750.2 -750.2

2018
NMDA receptor permeation: a light in the tunnel

David J A Wyllie , Stephen F Traynelis
Nature Neuroscience 15 ( 3) 343 -344

3
2012
Pharmacological insights obtained from structure–function studies of ionotropic glutamate receptors

Philip E Chen , David J A Wyllie
British Journal of Pharmacology 147 ( 8) 839 -853

87
2006
Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells.

Emma M Perkins , Yvonne L Clarkson , Daumante Suminaite , Alastair R Lyndon
Human Molecular Genetics 27 ( 15) 2614 -2627

11
2018
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

Sofia Papadia , Francesc X Soriano , Frédéric Léveillé , Marc-Andre Martel
Nature Neuroscience 11 ( 4) 476 -487

409
2008
Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1.

Jamie McQueen , Tomás J Ryan , Sean McKay , Katie Marwick
eLife 6 ( 6)

23
2017
Hypothermic modulation of human cortical neurons to explore a role for tau protein in neuroprotection

Nina M Rzechorzek , Peter Connick , Matthew R Livesey , Shyamanga Borooah
The Lancet 387

2016
GRIN2A-related disorders : genotype and functional consequence predict phenotype

Vincent Strehlow , Henrike O Heyne , Danique RM Vlaskamp , Katie FM Marwick
Brain 142 ( 1) 80 -92

51
2019
Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder

Laura Simões de Oliveira , Heather E O’Leary , Sarfaraz Nawaz , Rita Loureiro
Molecular Autism 15 ( 1) 28 -28

2024
TCN 201 selectively blocks GluN2A-containing NMDARs in a GluN1 co-agonist dependent but non-competitive manner.

S. Edman , S. McKay , L.J. MacDonald , M. Samadi
Neuropharmacology 63 ( 3) 441 -449

75
2012
Influence of GluN2 subunit identity on NMDA receptor function

D.J.A. Wyllie , M.R. Livesey , G.E. Hardingham
Neuropharmacology 74 4 -17

138
2013
Quantification of the Mg2+-induced potency shift of amantadine and memantine voltage-dependent block in human recombinant GluN1/GluN2A NMDARs

H.J. Otton , A. Lawson McLean , M.A. Pannozzo , C.H. Davies
Neuropharmacology 60 ( 2-3) 388 -396

23
2011
SynGAP isoforms exert opposing effects on synaptic strength

A.C. McMahon , M.W. Barnett , T.S. O'Leary , P.N. Stoney
Nature Communications 3 ( 1) 900 -900

52
2012
Single-channel properties of N-methyl-D-aspartate receptors containing chimaeric GluN2A/GluN2D subunits.

Timothy O'Leary , David J.A. Wyllie
Biochemical Society Transactions 37 ( 6) 1347 -1354

6
2009
Inhibition of recombinant GluN1/GluN2A and GluN1/GluN2B N-methyl-D-aspartate receptors by single malt whiskies

Hannah J. Otton , Ariane Janssen , David J.A. Wyllie
Biochemical Society Transactions 37 ( 6) 1423 -1425

2009
The Subtype of GluN2 C-terminal Domain Determines the Response to Excitotoxic Insults

Marc-André Martel , Tomás J. Ryan , Karen F.S. Bell , Jill H. Fowler
Neuron 74 ( 3) 543 -556

135
2012
Human embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegeneration.

Giles E. Hardingham , Rickie Patani , Paul Baxter , David J. Wyllie
Molecular Neurobiology 42 ( 1) 97 -102

18
2010