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Ejc Supplements 6 ( 12) 181 -182

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Activating PIK3CA mutations induce an EGFR/ERK paracrine signaling axis in basal-like breast cancer

CD Young , LJ Zimmerman , D Hoshino , L Formisano
Mol Cell Proteomics 14 1959 -1976

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Mapping Cell-to-cell Interactions from Spatially Resolved Transcriptomics Data.

J Zhu , Y Wang , WY Chang , A Malewska
Biorxiv: the Preprint Server for Biology

2023
Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling.

A B Hanker , N Mitin , R S Wilder , E P Henske
Oncogene 29 ( 3) 380 -391

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Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies

A. B. Hanker , A. D. Pfefferle , J. M. Balko , M. G. Kuba
Proceedings of the National Academy of Sciences of the United States of America 110 ( 35) 14372 -14377

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A platform of CDK4/6 inhibitor-resistant patient-derived breast cancer organoids illuminates mechanisms of resistance and therapeutic vulnerabilities

ABH Hanker , Sumanta Chatterjee , Yunguan Wang , Dan Ye
AACR; Cancer Res 82 ( 4 Suppl) Abstract nr PD2 -01

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A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics.

Etai Sapoznik , Bo-Jui Chang , Jaewon Huh , Robert J Ju
eLife 9 1 -39

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Romidepsin inhibits Ras-dependent growth transformation of NIH 3T3 fibroblasts and RIE-1 epithelial cells independently of Ras signaling inhibition

Ariella B Hanker , Kevin D Healy , Jean Nichols , Channing J Der
Journal of Molecular Signaling 4 ( 1) 5 -5

7
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In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2 -positive breast cancer

Michalina Janiszewska , Lin Liu , Vanessa Almendro , Yanan Kuang
Nature Genetics 47 ( 10) 1212 -1219

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Epigenetic repression of STING by MYC promotes immune evasion and resistance to immune checkpoint inhibitors in triple-negative breast cancer

Kyung-min Lee , Chang-Ching Lin , Alberto Servetto , Joonbeom Bae
Cancer Immunology Research 10 ( 7) 829 -843

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Abstract P5-17-09: A genome-wide CRISPR screen identifies PRMT5 as a novel therapeutic target in ER+/RB1-deficient breast cancer

Chang-Ching Lin , Tsung-Cheng Chang , Alberto Servetto , Kyung-min Lee
Cancer Research 82 ( 4\_Supplement) P5 -17

2022
Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity

Ariella B Hanker , Benjamin P Brown , Jens Meiler , Arnaldo Marín
Cancer Cell 39 ( 8) 1099 -1114

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gain-of-function kinase library screen identifies FGFR1 amplification as a mechanism of resistance to antiestrogens and CDK4/6 inhibitors in ER+ breast cancer

Luigi Formisano , Yao Lu , Valerie M Jansen , Joshua A Bauer
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Acquired secondary HER2 mutations enhance HER2/MAPK signaling and promote resistance to HER2 kinase inhibition in breast cancer

Arnaldo Marín , Abdullah Al Mamun , Hima Patel , Hiroaki Akamatsu
Cancer research 83 ( 18) 3145 -3158

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