引用次数
引用: 2,777
H-指数: 19
I10-指数 : 28
出版物: 104
Acquired secondary HER2 mutations enhance HER2/MAPK signaling and promote resistance to HER2 kinase inhibition in HER2-mutant breast cancer
Arnaldo Marin , Abdullah Al Mamun , Hiroaki Akamatsu , Dan Ye
bioRxiv 2022.09. 23.509246 -2022.09. 23.509246
1
2022
A spectrum of secondary mutations in HER2 augment breast cancer cell growth and reduce neratinib sensitivity in HER2-mutant breast cancer
Arnaldo Andres Marin , Abdullah Al Mamun , Hiroaki Akamatsu , Dan Ye
CANCER RESEARCH 82 ( 4)
2022
Abstract P4-01-02: A spectrum of secondary mutations in HER2 augment breast cancer cell growth and reduce neratinib sensitivity in HER2-mutant breast cancer
Arnaldo Andres Marin , Abdullah Al Mamun , Hiroaki Akamatsu , Dan Ye
Cancer Research 82 ( 4_Supplement) P4 -P4
2022
Correction: An Acquired HER2 T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant–Driven Breast Cancer
Ariella B Hanker , Monica Red Brewer , Jonathan H Sheehan , James P Koch
Cancer discovery 9 ( 2) 303 -303
2019
Immune cells infiltration and activation are higher in breast cancers resistant to antiestrogen therapy
Fabiana Napolitano , Dhivya R Sudhan , Yunguan Wang , Paula I González-Ericsson
Cancer Research 83 ( 7_Supplement) 3445 -3445
2023
Correction: Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer.
Ariella B Hanker , Mónica Valeria Estrada , Giampaolo Bianchini , Preston D Moore
Cancer research 79 ( 4) 873 -873
1
2019
ECM/Integrin signaling promotes resistance to the combination of HER2 and PI3K inhibitors in HER2+, PIK3CA-mutant breast cancer
Ariella B Hanker , Monica Valeria Estrada , Junfei Zhao , Feixiong Cheng
Cancer Research 76 ( 14 Supplement) 302 -302
2016
ZNF397 Deficiency Triggers TET2-driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
Yaru Xu , Yuqiu Yang , Zhaoning Wang , Martin Sjostrom
Cancer Discovery
2024
Mapping Cellular Interactions from Spatially Resolved Transcriptomics Data
James Zhu , Yunguan Wang , Woo Yong Chang , Alicia Malewska
bioRxiv 2023.09. 18.558298 -2023.09. 18.558298
1
2023
Proteogenomic Approaches for the Identification of NF1/Neurofibromin-depleted Estrogen Receptor–positive Breast Cancers for Targeted Treatment
Beom-Jun Kim , Ze-Yi Zheng , Jonathan T Lei , Matthew V Holt
Cancer Research Communications 3 ( 7) 1366 -1377
2
2023
Neratinib+ fulvestrant+ trastuzumab for HR-positive, HER2-negative, HER2-mutant metastatic breast cancer: outcomes and biomarker analysis from the SUMMIT trial
K Jhaveri , Lisa Diamond Eli , H Wildiers , Sara Alsterlind Hurvitz
Annals of Oncology 34 ( 10) 885 -898
15
2023
Human HER2 and PI3K H1047R cooperate to promote mammary tumorigenesis in vivo
Ariella B Hanker , Maria G Kuba , Violeta Sanchez , Cammie R Sutton
Cancer Research 72 ( 8_Supplement) 4875 -4875
3
2012
FGFR1 associates with gene promoters and regulates transcription in ER+/FGFR1-amplified breast cancer: Implications for endocrine resistance
Alberto Servetto , Rahul Kollipara , Luigi Formisano , Kyung-min Lee
Cancer Research 80 ( 16_Supplement) 1304 -1304
2020
Fibroblast growth factor receptor 1 associates with promoters genome-wide and regulates gene transcription in ER+/FGFR1-amplified breast cancer: Implications for endocrine resistance
Alberto Servetto , Rahul Kollipara , Luigi Formisano , Kyung-min Lee
CANCER RESEARCH 80 ( 4)
2020
FGFR1 signaling modulates estrogen-independent ER transcriptional activity in ER+/FGFR1-amplified breast cancer cells
Alberto Servetto , Luigi Formisano , Rahul Kollipara , Dhivya R Sudhan
Cancer Research 79 ( 13_Supplement) 4402 -4402
2019
Limiting mitochondrial plasticity by targeting DRP1 induces metabolic reprogramming and reduces breast cancer brain metastases
Pravat Kumar Parida , Mauricio Marquez-Palencia , Suvranil Ghosh , Nitin Khandelwal
Nature Cancer 4 ( 6) 893 -907
9
2023
Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness
Pravat Kumar Parida , Mauricio Marquez-Palencia , Vidhya Nair , Akash K Kaushik
Cell metabolism 34 ( 1) 90 -105. e7
46
2022
Mass spectrometry analysis of PIK3CA mutant mammary epithelial cells identifies EGFR as a paracrine effector of PI3K in basal-like breast cancer
Christian D Young , Lisa J Zimmerman , Michael L Gatza , Meghan M Morrison
Cancer Research 74 ( 19_Supplement) 970 -970
2014
Knock-in of PIK3CA mutations in MCF10A mammary epithelial cells modifies their proteomic profile to resemble basal-like breast cancer and stimulate EGFR-dependent cell proliferation
Christian D Young , Lisa J Zimmerman , Corbin A Whitwell , Ariella B Hanker
MOLECULAR CANCER RESEARCH 11
2013
HER2/PIK3CA (H1047R) transgenic mammary tumors develop acquired resistance to triple therapy with trastuzumab, pertuzumab and PI3K inhibitors via multiple mechanisms
Ariella B Hanker , Benjamin Bulen , Monica Red Brewer , Christian D Young
CANCER RESEARCH 75 ( 9)
2015
Dhivya R. Sudhan Kyung-min Lee Alberto Servetto Alshad S. Lalani Jens Meiler Sumanta Chatterjee, PhD Rebecca S. Cook Angel Guerrero-Zotano Saurabh Mendiratta Jonathan H. Sheehan Justin M. Balko Gregory Sliwoski Reto Fiolka Ralf Kittler David M Hyman Zhongming Zhao Feixiong Cheng Luigi Formisano David Solit Adam D. Pfefferle