Exogenous, but Not Endogenous, Glucocorticoids Augment Atherosclerosis in Mice

Nicholas S. Kirkby , Jonathan R. Seckl , Brian R. Walker , Patrick W. Hadoke
Arteriosclerosis, Thrombosis, and Vascular Biology 30 ( 11)

2010
Endothelial cyclooxygenase-1 paradoxically drives local vasoconstriction and atherogenesis despite underpinning prostacyclin generation.

Nicholas S. Kirkby , Jane A. Mitchell , Paula Urquhart , Anna Nicolaou
Science Advances 7 ( 12)

2021
Cardiorenal Tissues Express SARS-CoV-2 Entry Genes and Basigin (BSG/CD147) Increases With Age in Endothelial Cells

Blerina Ahmetaj-Shala , Ricky Vaja , Santosh S. Atanur , Peter M. George
JACC: Basic to Translational Science 5 ( 11) 1111 -1123

7
2020
Letter by Mitchell et al Regarding Article, "Urinary Prostaglandin Metabolites: An Incomplete Reckoning and a Flush to Judgment".

Jane A. Mitchell , Rebecca B. Knowles , Nicholas S. Kirkby , Daniel M. Reed
Circulation Research 122 ( 10)

2
2018
Cell-Specific Gene Deletion Reveals the Antithrombotic Function of COX1 and Explains the Vascular COX1/Prostacyclin Paradox.

Jane A. Mitchell , Fisnik Shala , Youssef Elghazouli , Timothy D. Warner
Circulation Research 125 ( 9) 847 -854

10
2019
Optical multichannel (optimul) platelet aggregometry in 96-well plates as an additional method of platelet reactivity testing.

Melissa V. Chan , Paul C. J. Armstrong , Francesco Papalia , Nicholas S. Kirkby
Platelets 22 ( 7) 485 -494

40
2011
Quantitative 3-Dimensional Imaging of Murine Neointimal and Atherosclerotic Lesions by Optical Projection Tomography

Nicholas S. Kirkby , Lucinda Low , Jonathan R. Seckl , Brian R. Walker
PLoS ONE 6 ( 2) e16906

16
2011
Morphology and vasoactive hormone profiles from endothelial cells derived from stem cells of different sources

Daniel M. Reed , Gabor Foldes , Nicholas S. Kirkby , Blerina Ahmetaj-Shala
Biochemical and Biophysical Research Communications 455 ( 3-4) 172 -177

7
2014
Drug-Free Platelets Can Act as Seeds for Aggregate Formation During Antiplatelet Therapy

Thomas Hoefer , Paul C. Armstrong , Michaela Finsterbusch , Melissa V. Chan
Arteriosclerosis, Thrombosis, and Vascular Biology 35 ( 10) 2122 -2133

13
2015
Cyclooxygenases and the cardiovascular system.

Jane A. Mitchell , Nicholas S. Kirkby , Blerina Ahmetaj-Shala , Paul C. Armstrong
Pharmacology & Therapeutics 217 107624

8
2021
Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction.

Paul C. J Armstrong , Nicholas S. Kirkby , Melissa V. Chan , Michaela Finsterbusch
Blood 126 ( 10)

15
2015
Inherited human group IVA cytosolic phospholipase A2 deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation

Nicholas S. Kirkby , Daniel M. Reed , Matthew L. Edin , Francesca Rauzi
The FASEB Journal 29 ( 11) 4568 -4578

18
2015
Differential role of pannexin-1/ATP/P2X7 axis in IL-1β release by human monocytes.

Katarzyna Parzych , Anna V. Zetterqvist , William R. Wright , Nicholas S. Kirkby
The FASEB Journal 31 ( 6) 2439 -2445

22
2017
Aspirin inhibits the production of proangiogenic 15(S)‐HETE by platelet cyclooxygenase‐1

Francesca Rauzi , Nicholas S. Kirkby , Matthew L. Edin , James Whiteford
The FASEB Journal 30 ( 12) 4256 -4266

31
2016
Ibuprofen arginate retains eNOS substrate activity and reverses endothelial dysfunction: implications for the COX-2/ADMA axis

Nicholas S. Kirkby , Abel Tesfai , Blerina Ahmetaj‐Shala , Hime H. Gashaw
The FASEB Journal 30 ( 12) 4172 -4179

7
2016
27
2017
56
2015