Histologic and Genomic Evaluation of Liver Cell Proliferation in the Chicken Egg Genotoxicity Assay (CEGA)

Tetyana Kobets , Michael J Iatropoulos , Klaus D Brunnemann , Dumitru A Iacobas

1
2017
Effects of oral exposure to bisphenol A on gene expression and global genomic DNA methylation in the prostate, female mammary gland, and uterus of NCTR Sprague-Dawley rats

Luísa Camacho , Mallikarjuna S. Basavarajappa , Ching-Wei Chang , Tao Han
Food and Chemical Toxicology 81 92 -103

15
2015
In ovo testing of flavor and fragrance materials in Turkey Egg Genotoxicity Assay (TEGA), comparison of results to in vitro and in vivo data

Tetyana Kobets , Jian-Dong Duan , Klaus D. Brunnemann , Michael J. Iatropoulos
Food and Chemical Toxicology 115 228 -243

7
2018
A no observed adverse effect level for DNA adduct formation in rat liver with prolonged dosing of the hepatocarcinogen 2-acetylaminofluorene

Gary M. Williams , Jian-Dong Duan , Michael J. Iatropoulos , Tetyana Kobets
Toxicology Research 4 ( 2) 233 -240

7
2015
MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis

Iryna Kindrat , Volodymyr Tryndyak , Aline de Conti , Svitlana Shpyleva
Oncotarget 7 ( 2) 1276 -1287

39
2016
Assessment of DNA Binding and Oxidative DNA Damage by Acrylonitrile in Two Rat Target Tissues of Carcinogenicity: Implications for the Mechanism of Action

Gary M. Williams , Tetyana Kobets , Jian-Dong Duan , Michael J. Iatropoulos
Chemical Research in Toxicology 30 ( 7) 1470 -1480

6
2017
Expression of Genes Encoding for Xenobiotic Metabolism After Exposure to Dialkylnitrosamines in the Chicken Egg Genotoxicity Alternative Model.

Tetyana Kobets , Michael J Iatropoulos , Jiandong D Duan , Klaus D Brunnemann
Toxicological Sciences 166 ( 1) 82 -96

6
2018
Adducts as Biomarkers of Effect of DNA-Reactive Carcinogens.

Tetyana Kobets , Gary M Williams
Toxicological Sciences 165 ( 1) 5 -5

1
2018
Sex-specific differences in genotoxic and epigenetic effects of 1,3-butadiene among mouse tissues

Lauren Lewis , Grace A. Chappell , Tetyana Kobets , Bridget E. O’Brian
Archives of Toxicology 93 ( 3) 791 -800

5
2019
Persistence of Furan-Induced Epigenetic Aberrations in the Livers of F344 Rats

Aline de Conti , Tetyana Kobets , Volodymyr Tryndyak , Sarah D. Burnett
Toxicological Sciences 144 ( 2) 217 -226

23
2015
Structure-Activity Relationships for DNA Damage by Alkenylbenzenes in Turkey Egg Fetal Liver.

Tetyana Kobets , Jian-Dong Duan , Klaus D. Brunnemann , Sylvain Etter
Toxicological Sciences 150 ( 2) 301 -311

22
2016
Dose- and Time-Dependent Epigenetic Changes in the Livers of Fisher 344 Rats Exposed to Furan

Aline de Conti , Tetyana Kobets , Claudia Escudero-Lourdes , Beverly Montgomery
Toxicological Sciences 139 ( 2) 371 -380

30
2014
Epigenetic Events Determine Tissue-Specific Toxicity of Inhalational Exposure to the Genotoxic Chemical 1,3-Butadiene in Male C57BL/6J Mice

Grace Chappell , Tetyana Kobets , Bridget O’Brien , Natalia Tretyakova
Toxicological Sciences 142 ( 2) 375 -384

20
2014
Assessment and characterization of DNA adducts produced by alkenylbenzenes in fetal turkey and chicken livers.

Tetyana Kobets , Alexander T. Cartus , Julia A. Fuhlbrueck , Alexander Brengel
Food and Chemical Toxicology 129 424 -433

2
2019
Review of the evidence for thresholds for DNA-Reactive and epigenetic experimental chemical carcinogens

Tetyana Kobets , Gary M. Williams
Chemico-Biological Interactions 301 88 -111

12
2019
Mechanisms of DNA-reactive and epigenetic chemical carcinogens: applications to carcinogenicity testing and risk assessment

Tetyana Kobets , Michael J. Iatropoulos , Gary M. Williams
Toxicology Research 8 ( 2) 123 -145

6
2019
DNA-damaging activities of twenty-four structurally diverse unsubstituted and substituted cyclic compounds in embryo-fetal chicken livers.

Tetyana Kobets , Jian-Dong Duan , Klaus D. Brunnemann , Esther Vock
Mutation Research 844 10 -24

2
2019