Assessment of DNA Copy Number Alterations in Mouse and Human Hepatocellular Carcinoma
Grace Chappell
2014
Integration of Evidence to Evaluate the Potential for Neurobehavioral Effects Following Exposure to USFDA-Approved Food Colors
Harvey Clewell , James Rathman , Grace Chappell , Tracy Greene
Food and Chemical Toxicology 151 112097 -112097
2
2021
RE: Response to the Office of Environmental Health Hazard Assessment on comments related to Gentry et al. (2021).
Harvey Clewell , James Rathman , Grace Chappell , Tracy Greene
Food and Chemical Toxicology 152 112202
2021
Characterization of copy number alterations in a mouse model of fibrosis‐associated hepatocellular carcinoma reveals concordance with human disease
Grace Chappell , Grace O. Silva , Takeki Uehara , Igor P. Pogribny
Cancer Medicine 5 ( 3) 574 -585
2
2016
Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: A systematic literature review.
Grace Chappell , Igor P. Pogribny , Kathryn Z. Guyton , Ivan Rusyn
Mutation Research-reviews in Mutation Research 768 27 -45
151
2016
Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice
Grace Chappell , Kristy Kutanzi , Takeki Uehara , Volodymyr Tryndyak
International Journal of Cancer 134 ( 12) 2778 -2788
26
2014
A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates.
Mina Suh , Deborah Proctor , Grace Chappell , Julia Rager
Toxicology 50 -67
7
2018
Inbreeding depression and inbreeding avoidance in a natural population of guppies (Poecilia reticulata).
Ashley M. Johnson , Grace Chappell , Anna C. Price , F. Helen Rodd
Ethology 116 ( 5) 448 -457
34
2010
Epigenetic Events Determine Tissue-Specific Toxicity of Inhalational Exposure to the Genotoxic Chemical 1,3-Butadiene in Male C57BL/6J Mice
Grace Chappell , Tetyana Kobets , Bridget O’Brien , Natalia Tretyakova
Toxicological Sciences 142 ( 2) 375 -384
20
2014
Differentially expressed MicroRNAs provide mechanistic insight into fibrosis-associated liver carcinogenesis in mice.
April K. Marrone , Svitlana Shpyleva , Grace Chappell , Volodymyr Tryndyak
Molecular Carcinogenesis 55 ( 5) 808 -817
10
2016
An Adverse Outcome Pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events.
Deborah M. Proctor , Mina Suh , Grace Chappell , Susan J. Borghoff
Regulatory Toxicology and Pharmacology 96 30 -40
8
2018
Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans.
Chad M. Thompson , Mina Suh , Deborah M. Proctor , Grace Chappell
Regulatory Toxicology and Pharmacology 96 178 -189
4
2018
Chemistry domain of applicability evaluation against existing estrogen receptor high-throughput assay-based activity models
Mark D Nelms , Todor Antonijevic , Caroline Ring , Danni L Harris
Frontiers in Toxicology 6 1346767 -1346767
2024
Optimizing androgen receptor prioritization using high-throughput assay-based activity models
Ronnie Joe Bever , Stephen W Edwards , Todor Antonijevic , Mark D Nelms
Frontiers in Toxicology 6 1347364 -1347364
2024
Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: An update of a systematic literature review
Samantha Goodman , Grace Chappell , Kathryn Z Guyton , Igor P Pogribny
Mutation Research/reviews in Mutation Research 789 108408 -108408
13
2022
The microRNA profile is altered in fibrosis-associated hepatocarcinogenesis in mice
April K Marrone , Volodymyr Tryndyak , Grace Chappell , Frederick A Beland
Cancer Research 74 ( 19_Supplement) 5227 -5227
1
2014
Transcriptomic analyses of livers from mice exposed to 1,4-dioxane for up to 90 days to assess potential mode(s) of action underlying liver tumor development
G.A. Chappell , L.C. Haws , M.M. Heintz
Current Research in Toxicology 2 30 -41
2021
Lack of potential carcinogenicity for steviol glycosides - Systematic evaluation and integration of mechanistic data into the totality of evidence
D.S. Wikoff , G.A. Chappell , C.L. Doepker , S.J. Borghoff
Food and Chemical Toxicology 150 112045 -112045
2021
Lack of potential carcinogenicity for aspartame - Systematic evaluation and integration of mechanistic data into the totality of the evidence.
G.A. Chappell , S.J. Borghoff , L.L. Pham , C.L. Doepker
Food and Chemical Toxicology 135 110898 -110898
5
2020
Systematic assessment of mechanistic data for FDA-certified food colors and neurodevelopmental processes
G.A. Chappell , J.K. Britt , S.J. Borghoff
Food and Chemical Toxicology 140 111310
4
2020