引用次数
引用: 8,383
H-指数: 46
I10-指数 : 99
出版物: 601
Chemical kinetics for drug discovery to combat protein aggregation diseases.
Paolo Arosio , Michele Vendruscolo , Christopher M. Dobson , Tuomas P.J. Knowles
Trends in Pharmacological Sciences 35 ( 3) 127 -135
135
2014
Time evolution of amyloid fibril length distribution described by a population balance model
Paolo Arosio , Marten Beeg , Lucrece Nicoud , Massimo Morbidelli
Chemical Engineering Science 78 21 -32
29
2012
Analysis of the length distribution of amyloid fibrils by centrifugal sedimentation
Paolo Arosio , Tommy Cedervall , Tuomas P.J. Knowles , Sara Linse
Analytical Biochemistry 504 7 -13
8
2016
Role of urea on recombinant Apo A-I stability and its utilization in anion exchange chromatography.
Monica Angarita , Paolo Arosio , Thomas Müller-Späth , Daniel Baur
Journal of Chromatography A 1354 18 -25
4
2014
A Colloidal Description of Intermolecular Interactions Driving Fibril-Fibril Aggregation of a Model Amphiphilic Peptide
Marta Owczarz , Anna C. Motta , Massimo Morbidelli , Paolo Arosio
Langmuir 31 ( 27) 7590 -7600
10
2015
Density-gradient-free microfluidic centrifugation for analytical and preparative separation of nanoparticles.
Paolo Arosio , Thomas Müller , L. Mahadevan , Tuomas P. J. Knowles
Nano Letters 14 ( 5) 2365 -2371
56
2014
Kinetic Analysis of the Multistep Aggregation Mechanism of Monoclonal Antibodies
Lucrèce Nicoud , Paolo Arosio , Margaux Sozo , Andrew Yates
Journal of Physical Chemistry B 118 ( 36) 10595 -10606
33
2014
Sulfate Anion Delays the Self-Assembly of Human Insulin by Modifying the Aggregation Pathway
Marta Owczarz , Paolo Arosio
Biophysical Journal 107 ( 1) 197 -207
12
2014
Effect of primary particle morphology on the structure of gels formed in intense turbulent shear.
Paolo Arosio , Delong Xie , Hua Wu , Leonie Braun
Langmuir 26 ( 9) 6643 -6649
10
2010
Interaction of the molecular chaperone DNAJB6 with growing amyloid-beta 42 (Aβ42) aggregates leads to sub-stoichiometric inhibition of amyloid formation
Cecilia Månsson , Paolo Arosio , Rasha Hussein , Harm H. Kampinga
Journal of Biological Chemistry 289 ( 45) 31066 -31076
93
2014
Particle-Based Monte-Carlo Simulations of Steady-State Mass Transport at Intermediate Péclet Numbers
Thomas Müller , Paolo Arosio , Luke Rajah , Samuel I. A. Cohen
International Journal of Nonlinear Sciences and Numerical Simulation 17 175 -183
10
2016
End-to-end self-assembly of RADA 16-I nanofibrils in aqueous solutions.
Paolo Arosio , Marta Owczarz , Hua Wu , Alessandro Butté
Biophysical Journal 102 ( 7) 1617 -1626
35
2012
A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
Samuel I A Cohen , Paolo Arosio , Jenny Presto , Firoz Roshan Kurudenkandy
Nature Structural & Molecular Biology 22 ( 3) 207 -213
367
2015
A multiscale view of therapeutic protein aggregation: a colloid science perspective.
Lucrèce Nicoud , Marta Owczarz , Paolo Arosio , Massimo Morbidelli
Biotechnology Journal 10 ( 3) 367 -378
36
2015
Population Balance Modeling of Antibodies Aggregation Kinetics
Paolo Arosio , Simonetta Rima , Marco Lattuada , Massimo Morbidelli
Journal of Physical Chemistry B 116 ( 24) 7066 -7075
56
2012
The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model
Vaishali Kakkar , Cecilia Månsson , Eduardo P De Mattos , Steven Bergink
Molecular Cell 62 ( 2) 272 -283
79
2016
Biophysical approaches for the study of interactions between molecular chaperones and protein aggregates
Maya A. Wright , Francesco A. Aprile , Paolo Arosio , Michele Vendruscolo
Chemical Communications 51 ( 77) 14425 -14434
22
2015
Dynamics of protein aggregation and oligomer formation governed by secondary nucleation
Thomas C. T. Michaels , Hamish W. Lazell , Paolo Arosio , Tuomas P. J. Knowles
Journal of Chemical Physics 143 ( 5) 054901 -054901
28
2015
An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer's disease.
Johnny Habchi , Paolo Arosio , Michele Perni , Ana Rita Costa
Science Advances 2 ( 2)
194
2016
In vitro aggregation behavior of a non-amyloidogenic λ light chain dimer deriving from U266 multiple myeloma cells.
Paolo Arosio , Marta Owczarz , Thomas Müller-Späth , Paola Rognoni
PLOS ONE 7 ( 3)
12
2012