Alina Guna
机构: K99/R00 Pathway to Independence Fellow
每年引用次数
引用次数
引用: 1,464
H-指数: 15
I10-指数 : 16
出版物: 21
Membrane protein biosynthesis at the endoplasmic reticulum
Alina-Ioana Guna
University of Cambridge
2018
WNK1 is an assembly factor for the human ER membrane protein complex.
Michael J. Sweredoski , Annie Moradian , Robert S. Oania , Rebecca M. Voorhees
Molecular Cell
1
2021
Comparative mapping of the 22q11.2 deletion region and the potential of simple model organisms
Alina Guna , Nancy J. Butcher , Anne S. Bassett
Journal of Neurodevelopmental Disorders 7 ( 1) 18 -18
89
2015
The ER membrane protein complex is a transmembrane domain insertase
Alina Guna , Norbert Volkmar , John C. Christianson , Ramanujan S. Hegde
Science 359 ( 6374) 470 -473
118
2018
Elucidating the diagnostic odyssey of 22q11.2 deletion syndrome.
Lisa D. Palmer , Nancy J. Butcher , Erik Boot , Kathleen A. Hodgkinson
American Journal of Medical Genetics Part A 176 ( 4) 936 -944
19
2018
Response to clozapine in a clinically identifiable subtype of schizophrenia
Nancy J. Butcher , Wai Lun Alan Fung , Laura Fitzpatrick , Alina Guna
British Journal of Psychiatry 206 ( 6) 484 -491
40
2015
Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology
Alessandra Stangherlin , David C. S. Wong , Silvia Barbiero , Joseph L. Watson
bioRxiv
17
2020
Transmembrane Domain Recognition during Membrane Protein Biogenesis and Quality Control
Alina Guna , Ramanujan S. Hegde
Current Biology 28 ( 8)
82
2018
A Highly Porous Metal-Organic Framework System to Deliver Payloads for Gene Knockdown
Michelle H. Teplensky , Marcus Fantham , Chetan Poudel , Colin Hockings
Chem 5 ( 11) 2926 -2941
49
2019
Differential Modes of Orphan Subunit Recognition for the WRB/CAML Complex.
Alison J. Inglis , Katharine R. Page , Alina Guna , Rebecca M. Voorhees
Cell Reports 30 ( 11)
7
2020
EMC Is Required to Initiate Accurate Membrane Protein Topogenesis
Patrick J. Chitwood , Szymon Juszkiewicz , Alina Guna , Sichen Shao
Cell 175 ( 6) 1507 -1519
172
2018
Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq
Joseph M Replogle , Reuben A Saunders , Angela N Pogson , Jeffrey A Hussmann
Cell 185 ( 14) 2559 -2575
70
2022
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors
Joseph M Replogle , Jessica L Bonnar , Angela N Pogson , Christina R Liem
Elife 11 e81856
3
2022
MTCH2 is a mitochondrial outer membrane protein insertase
Alina Guna , Taylor A Stevens , Alison J Inglis , Joseph M Replogle
Science 378 ( 6617) 317 -322
55
2022
Coupled protein quality control during nonsense-mediated mRNA decay
Alison J Inglis , Alina Guna , Ángel Gálvez-Merchán , Akshaye Pal
Journal of Cell Science 136 ( 10) jcs261216 -jcs261216
15
2023
A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens
Alina Guna , Katharine R Page , Joseph M Replogle , Theodore K Esantsi
BMC genomics 24 ( 1) 651 -651
5
2023
Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology
Gayathri Muthukumar , Taylor A Stevens , Alison J Inglis , Theodore K Esantsi
Molecular Cell
1
2024
Macromolecular condensation buffers intracellular water potential
Joseph L Watson , Estere Seinkmane , Christine T Styles , Andrei Mihut
Nature 623 ( 7988) 842 -852
21
2023
A genome-wide optical pooled screen reveals regulators of cellular antiviral responses
Rebecca J Carlson , Michael D Leiken , Alina Guna , Nir Hacohen
Proceedings of the National Academy of Sciences 120 ( 16) e2210623120 -e2210623120
14
2023
A TAle of two pathways: Tail-anchored protein insertion at the endoplasmic reticulum
Alina Guna , Masami Hazu , Giovani Pinton Tomaleri , Rebecca M Voorhees
Cold Spring Harbor Perspectives in Biology 15 ( 3) a041252 -a041252
9
2023