Pietro Sormanni
机构: Royal Society University Research Fellow, Department of Chemistry, University of Cambridge.
每年引用次数
引用次数
引用: 3,698
H-指数: 30
I10-指数 : 52
出版物: 72
Attentive cross-modal paratope prediction
Pietro Sormanni , Petar Veličković , Andreea Deac
arXiv: Machine Learning
40
2018
Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases
Johnny Habchi , Pietro Sormanni , Michele Vendruscolo , Klara Kulenkampff
Nature Reviews Chemistry 5 ( 4) 277 -294
2021
Rationally Designed Bicyclic Peptides Prevent the Conversion of Aβ42 Assemblies Into Fibrillar Structures.
Pietro Sormanni , Michele Vendruscolo , Tatsuya Ikenoue , Francesco A. Aprile
Frontiers in Neuroscience 15 623097 -623097
2021
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease.
Michele Perni , Annemieke Van der Goot , Ryan Limbocker , Tjakko J Van Ham
Frontiers in Cell and Developmental Biology 9 552549 -552549
2021
Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery
Michele Perni , Pavan K Challa , Julius B Kirkegaard , Ryan Limbocker
Journal of Neuroscience Methods 306 57 -67
48
2018
Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins
Pietro Sormanni , Francesco A. Aprile , Michele Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America 112 ( 32) 9902 -9907
114
2015
A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer's disease.
Tatsuya Ikenoue , Francesco A. Aprile , Pietro Sormanni , Francesco S. Ruggeri
Scientific Reports 10 ( 1) 15280 -15280
3
2020
A Rationally Designed Hsp70 Variant Rescues the Aggregation-Associated Toxicity of Human IAPP in Cultured Pancreatic Islet β-Cells.
Marie Bongiovanni , Francesco Aprile , Pietro Sormanni , Michele Vendruscolo
International Journal of Molecular Sciences 19 ( 5) 1443
9
2018
Supersaturated proteins are enriched at synapses and underlie cell and tissue vulnerability in Alzheimer's disease.
Rosie Freer , Pietro Sormanni , Prajwal Ciryam , Burkhard Rammner
Heliyon 5 ( 11)
7
2019
Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Tanguy Le Marchand , Matteo de Rosa , Nicola Salvi , Benedetta Maria Sala
Nature Communications 9 ( 1) 1658 -1658
29
2018
Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity
Adnane Achour , Luca Broggini , Xiao Han , Renhua Sun
FEBS Journal 287 ( 3) 546 -560
2
2020
Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming.
Nabeel Ahmed , Pietro Sormanni , Prajwal Ciryam , Michele Vendruscolo
Scientific Reports 9 ( 1) 6256 -6256
8
2019
In vitro and in silico assessment of the developability of a designed monoclonal antibody library.
Adriana-Michelle Wolf Pérez , Pietro Sormanni , Jonathan Sonne Andersen , Laila Ismail Sakhnini
mAbs 11 ( 2) 388 -400
20
2019
A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data
Ajeet K. Sharma , Pietro Sormanni , Nabeel Ahmed , Prajwal Ciryam
PLOS Computational Biology 15 ( 5) e1007070
24
2019
Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Carlo Camilloni , Benedetta Maria Sala , Pietro Sormanni , Riccardo Porcari
Scientific Reports 6 ( 1) 25559 -25559
57
2016
Fibrillogenic propensity of the GroEL apical domain: A Janus-faced minichaperone
Jin Chen , Hisashi Yagi , Pietro Sormanni , Michele Vendruscolo
FEBS Letters 586 ( 8) 1120 -1127
14
2012
Proteome-wide observation of the phenomenon of life on the edge of solubility
Giulia Vecchi , Pietro Sormanni , Benedetta Mannini , Andrea Vandelli
Proceedings of the National Academy of Sciences of the United States of America 117 ( 2) 1015 -1020
81
2020
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers.
Francesco A. Aprile , Pietro Sormanni , Marina Podpolny , Shianne Chhangur
Proceedings of the National Academy of Sciences of the United States of America 117 ( 24) 13509 -13518
43
2020
A Rational Design Strategy for the Selective Activity Enhancement of a Molecular Chaperone toward a Target Substrate.
Francesco A. Aprile , Pietro Sormanni , Michele Vendruscolo
Biochemistry 54 ( 32) 5103 -5112
27
2015
Rationally Designed Antibodies as Research Tools to Study the Structure-Toxicity Relationship of Amyloid-β Oligomers.
Ryan Limbocker , Benedetta Mannini , Rodrigo Cataldi , Shianne Chhangur
International Journal of Molecular Sciences 21 ( 12) 4542
4
2020