NOVEL PDE4 INHIBITORS

Ke HENGMING , Gurpreet KAUR , Binghe WANG , Shi Long ZHENG

2019
One-Pot Synthesis of Seven-membered Heterocyclic Derivatives of Diazepines Involving Copper-Catalyzed Rearrangement Cascade Allyl-Amination

Yuepeng Chen , Xinglei Liu , Wei Shi , Shilong Zheng
Journal of Organic Chemistry 85 ( 8) 5146 -5157

1
2020
Development of a bioavailable boron-containing PI-103 Bioisostere, PI-103BE.

Lan Luo , Qiu Zhong , Shanchun Guo , Changde Zhang
Bioorganic & Medicinal Chemistry Letters 30 ( 14) 127258

3
2020
Design, synthesis, and evaluation of novel heteroaromatic analogs of curcumin as anti-cancer agents

Nawras Samaan , Qiu Zhong , Jayjoel Fernandez , Guanglin Chen
European Journal of Medicinal Chemistry 75 123 -131

58
2014
Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells.

Quan Jiang , Florastina Payton-Stewart , Steven Elliott , Jennifer Driver
Journal of Medicinal Chemistry 53 ( 16) 6153 -6163

36
2010
19
2015
Biocompatible Boron-Containing Prodrugs of Belinostat for the Potential Treatment of Solid Tumors

Shilong Zheng , Shanchun Guo , Qiu Zhong , Changde Zhang
ACS Medicinal Chemistry Letters 9 ( 2) 149 -154

35
2018
Nitrogen-containing derivatives of O-tetramethylquercetin: Synthesis and biological profiles in prostate cancer cell models

Pravien Rajaram , Ziran Jiang , Guanglin Chen , Alyssa Rivera
Bioorganic Chemistry 87 227 -239

2019
Fulvestrant-3 Boronic Acid (ZB716): An Orally Bioavailable Selective Estrogen Receptor Downregulator (SERD)

Jiawang Liu , Shilong Zheng , Victoria L. Akerstrom , Chester Yuan
Journal of Medicinal Chemistry 59 ( 17) 8134 -8140

60
2016
Design, synthesis, and biological evaluation of 1,9-diheteroarylnona-1,3,6,8-tetraen-5-ones as a new class of anti-prostate cancer agents

Xiaojie Zhang , Rubing Wang , German Ruiz Perez , Guanglin Chen
Bioorganic & Medicinal Chemistry 24 ( 19) 4692 -4700

5
2016
3-O-Substituted-3',4',5'-trimethoxyflavonols: Synthesis and cell-based evaluation as anti-prostate cancer agents.

Xiang Li , Maizie Lee , Guanglin Chen , Qiang Zhang
Bioorganic & Medicinal Chemistry 25 ( 17) 4768 -4777

4
2017
5- or/and 20-O-alkyl-2,3-dehydrosilybins: Synthesis and biological profiles on prostate cancer cell models.

Bao Vue , Xiaojie Zhang , Timmy Lee , Nandini Nair
Bioorganic & Medicinal Chemistry 25 ( 17) 4845 -4854

6
2017
Optimized synthesis and antiproliferative activity of desTHPdactylolides.

Guanglin Chen , Rubing Wang , Bao Vue , Manee Patanapongpibul
Bioorganic & Medicinal Chemistry 26 ( 12) 3514 -3520

6
2018
Optimization of diarylpentadienones as chemotherapeutics for prostate cancer.

Manee Patanapongpibul , Changde Zhang , Guanglin Chen , Shanchun Guo
Bioorganic & Medicinal Chemistry 26 ( 16) 4751 -4760

1
2018
Ligands of Therapeutic Utility for the Liver X Receptors

Rajesh Komati , Dominick Spadoni , Shilong Zheng , Jayalakshmi Sridhar
Molecules 22 ( 1) 88

41
2017