Christian Wölk
机构: Senior Scientist, Institute of Pharmacy, Leipzig University
每年引用次数
引用次数
引用: 703
H-指数: 16
I10-指数 : 32
出版物: 64
Kationische Lipide für den Gentransfer - Synthese und Charakterisierung neuer Lipide auf Malonamidbasis sowie Beiträge zur Untersuchung des Aggregationsverhaltens im wässrigen Milieu
Christian Wölk
Universitäts- und Landesbibliothek Sachsen-Anhalt
2014
Lipid domain formation and non-lamellar structures associated with varied lysylphosphatidylglycerol analogue content in a model Staphylococcal plasma membrane.
Gerd Hause , Bruno Demé , Christian Wölk , Richard D. Harvey
Biochimica et Biophysica Acta 1863 ( 5) 183571 -183571
2021
Enhanced Efficacy and Drug Delivery with Lipid Coated Mesoporous Silica Nanoparticles in Cancer Therapy.
Jana Brüßler , Udo Bakowsky , Christian Wölk , Christian Wölk
European Journal of Pharmaceutics and Biopharmaceutics 165 31 -40
24
2021
A focus on critical aspects of uptake and transport of milk-derived extracellular vesicles across the Caco-2 intestinal barrier model.
Michaela Schulz-Siegmund , Gerd Hause , Cica Vissiennon , Christian Wölk
European Journal of Pharmaceutics and Biopharmaceutics
2021
Structures of malonic acid diamide/phospholipid composites and their lipoplexes
Christopher Janich , Stephanie Taßler , Annette Meister , Gerd Hause
Soft Matter 12 ( 27) 5854 -5866
12
2016
Interaction of DNA with Cationic Lipid Mixtures-Investigation at Langmuir Lipid Monolayers.
Christopher Janich , André Hädicke , Udo Bakowsky , Gerald Brezesinski
Langmuir 33 ( 39) 10172 -10183
8
2017
Overcoming the polycation dilemma - Explorative studies to characterise the efficiency and biocompatibility of newly designed lipofection reagents.
Julia Giselbrecht , Christopher Janich , Shashank Reddy Pinnapireddy , Gerd Hause
International Journal of Pharmaceutics 541 81 -92
4
2018
Establishment of a Synthetic In Vitro Lung Surfactant Model for Particle Interaction Studies on a Langmuir Film Balance.
Julia J. Schüer , Alexej Arndt , Christian Wölk , Shashank R. Pinnapireddy
Langmuir 36 ( 17) 4808 -4819
2
2020
Composites of malonic acid diamides and phospholipids--Impact of lipoplex stability on transfection efficiency.
Christopher Janich , Christian Wölk , Frank Erdmann , Thomas Groth
Journal of Controlled Release 220 295 -307
11
2015
Structure-Function Relationships of New Lipids Designed for DNA Transfection
Matthias Dittrich , Martin Heinze , Christian Wölk , Sergio S. Funari
ChemPhysChem 12 ( 12) 2328 -2337
17
2011
Composites of malonic acid diamides and phospholipids – Structural parameters for optimal transfection efficiency in A549 cells
Christopher Janich , Christian Wölk , Stephanie Taßler , Simon Drescher
European Journal of Lipid Science and Technology 116 ( 9) 1184 -1194
12
2014
The Impact of Alkyl-Chain Purity on Lipid-Based Nucleic Acid Delivery Systems - Is the Utilization of Lipid Components with Technical Grade Justified?
Dorota Pawlowska , Christopher Janich , Andreas Langner , Bodo Dobner
ChemPhysChem 20 ( 16) 2110 -2121
2
2019
Phase Diagram for a Lysyl-Phosphatidylglycerol Analogue in Biomimetic Mixed Monolayers with Phosphatidylglycerol: Insights into the Tunable Properties of Bacterial Membranes.
Christian Wölk , Hala Youssef , Thomas Guttenberg , Helene Marbach
ChemPhysChem 21 ( 8) 702 -706
1
2020
Lamellar versus micellar structures-aggregation behavior of a three-chain cationic lipid designed for nonviral polynucleotide transfer
Christian Wölk , Christopher Janich , Dorota Pawlowska , Simon Drescher
ChemPhysChem 16 ( 10) 2115 -2126
9
2015
Cover Picture: Lamellar versus Micellar Structures—Aggregation Behavior of a Three-Chain Cationic Lipid Designed for Nonviral Polynucleotide Transfer (ChemPhysChem 10/2015)
Christian Wölk , Christopher Janich , Dorota Pawlowska , Simon Drescher
ChemPhysChem 16 ( 10) 2025 -2025
2015
New Micellar Transfection Agents
Christian Wölk , Dorota Pawlowska , Simon Drescher , Anna Auerswald
Langmuir 30 ( 17) 4905 -4915
8
2014
DNA Delivery Systems Based on Peptide-Mimicking Cationic Lipids-The Effect of the Co-Lipid on the Structure and DNA Binding Capacity.
Stephanie Tassler , Bodo Dobner , Lisa Lampp , Robert Ziółkowski
Langmuir 35 ( 13) 4613 -4625
1
2019
Synthesis and DNA transfection properties of new head group modified malonic acid diamides.
Christian Wölk , Martin Heinze , Patrick Kreideweiß , Matthias Dittrich
International Journal of Pharmaceutics 409 ( 1) 46 -56
21
2011
Lysine-based amino-functionalized lipids for gene transfection: 3D phase behaviour and transfection performance.
Stephanie Tassler , Dorota Pawlowska , Christopher Janich , Julia Giselbrecht
Physical Chemistry Chemical Physics 20 ( 25) 17393 -17405
2
2018
Lysine-based amino-functionalized lipids for gene transfection: the influence of the chain composition on 2D properties.
Stephanie Tassler , Dorota Pawlowska , Christopher Janich , Bodo Dobner
Physical Chemistry Chemical Physics 20 ( 10) 6936 -6944
5
2018