Deletion of microsomal prostaglandin E2 (PGE2) synthase-1 reduces inducible and basal PGE2 production and alters the gastric prostanoid profile.
Louise Boulet , Marc Ouellet , Kevin P. Bateman , Diane Ethier
Journal of Biological Chemistry 279 ( 22) 23229 -23237
111
2004
Using mass spectrometry to study the photo-affinity labeling of protein tyrosine phosphatase 1B
Tammy LeRiche , Kathryn Skorey , Patrick Roy , Dan McKay
International Journal of Mass Spectrometry 238 ( 2) 99 -106
5
2004
Rapid measurement of deuterium-labeled long-chain fatty acids in plasma by HPLC-ESI-MS.
Sébastien Gagné , Sheldon Crane , Zheng Huang , Chun Sing Li
Journal of Lipid Research 48 ( 1) 252 -259
26
2007
Metabolic activation of indole-containing prostaglandin D2 receptor 1 antagonists: impacts of glutathione trapping and glucuronide conjugation on covalent binding.
Jean-François Lévesque , Stephen H. Day , Nathalie Chauret , Carmai Seto
Bioorganic & Medicinal Chemistry Letters 17 ( 11) 3038 -3043
25
2007
`All-in-One' analysis for metabolite identification using liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry with collision energy switching
Mark Wrona , Timo Mauriala , Kevin P. Bateman , Russell J. Mortishire-Smith
Rapid Communications in Mass Spectrometry 19 ( 18) 2597 -2602
151
2005
Simultaneous analysis of prostanoids using liquid chromatography/high-field asymmetric waveform ion mobility spectrometry/tandem mass spectrometry†
Jin Wu , Timo Mauriala , Patsy Clark , Randy W. Purves
Rapid Communications in Mass Spectrometry 20 ( 10) 1504 -1510
42
2006
MSE with mass defect filtering for in vitro and in vivo metabolite identification.
Kevin P. Bateman , Jose Castro-Perez , Mark Wrona , John P. Shockcor
Rapid Communications in Mass Spectrometry 21 ( 9) 1485 -1496
298
2007
A strategy for identification of drug metabolites from dried blood spots using triple-quadrupole/linear ion trap hybrid mass spectrometry.
Timo Mauriala , Nathalie Chauret , Renata Oballa , Deborah A. Nicoll-Griffith
Rapid Communications in Mass Spectrometry 19 ( 14) 1984 -1992
45
2005
Fractional mass filtering as a means to assess circulating metabolites in early human clinical studies
Philip R. Tiller , Sean Yu , Kevin P. Bateman , Jose Castro-Perez
Rapid Communications in Mass Spectrometry 22 ( 22) 3510 -3516
38
2008
Probing the microheterogeneity of O-specific chains from Yersinia ruckeri using capillary zone electrophoresis/electrospray mass spectrometry.
Kevin P. Bateman , Joseph H. Banoub , Pierre Thibault
Electrophoresis 17 ( 12) 1818 -1828
15
1996
Disposable Emitters for On-line Capillary Zone Electrophoresis/Nanoelectrospray Mass Spectrometry
Kevin P. Bateman , Robert L. White , Pierre Thibault
Rapid Communications in Mass Spectrometry 11 ( 3) 307 -315
96
1997
Phosphopeptide isomer separation using capillary zone electrophoresis for the study of protein kinases and phosphatases.
Tanya N. Gamble , Chidambaram Ramachandran , Kevin P. Bateman
Analytical Chemistry 71 ( 16) 3469 -3476
27
1999
Digitally Enabled, Patient-Centric Clinical Trials: Shifting the Drug Development Paradigm.
Marissa F. Dockendorf , Bryan J. Hansen , Kevin P. Bateman , Matthew Moyer
Clinical and Translational Science 14 ( 2) 445 -459
1
2021
An Integrated Strategy for Implementation of Dried Blood Spots in Clinical Development Programs.
Prajakti A. Kothare , Kevin P. Bateman , Marissa Dockendorf , Julie Stone
Aaps Journal 18 ( 2) 519 -527
29
2016
Enabling Efficient Late-Stage Functionalization of Drug-Like Molecules with LC-MS and Reaction-Driven Data Processing
Huifang Yao , Yong Liu , Sriram Tyagarajan , Eric Streckfuss
European Journal of Organic Chemistry 2017 ( 47) 7122 -7126
6
2017
Quantitation of a Therapeutic Antibody in Serum Using Intact Sequential Affinity Capture, Trypsin Digestion, and LC-MS/MS.
Lisa A. Vasicek , Daniel S. Spellman , SuChun Hsieh , Wolfgang Seghezzi
Analytical Chemistry 90 ( 1) 866 -871
10
2018
Development of generic liquid chromatography-mass spectrometry methods using experimental design
Carmai Seto , Kevin P. Bateman , Berton Gunter
Journal of the American Society for Mass Spectrometry 13 ( 1) 2 -9
22
2002
Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524).
Claudio F. Sturino , Gary O'Neill , Nicolas Lachance , Michael Boyd
Journal of Medicinal Chemistry 50 ( 4) 794 -806
197
2007
High-Resolution Mass Spectrometry and Drug Metabolite Identification
Russell J. Mortishire-Smith , Haiying Zhang , Kevin P. Bateman
Mass Spectrometry in Drug Metabolism and Disposition 407 -448
7
2011
Correlation-based detection of spectral information using microliter volumes, in-torch vaporization (ITV) sample introduction and inductively coupled plasma atomic emission spectrometry with photodiode array detection
Vassili Karanassios , Kevin P. Bateman , Graeme A. Spiers
Spectrochimica Acta Part B: Atomic Spectroscopy 49 ( 10) 989 -1005
10
1994