A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity

Louisa Nelson , Anthony Tighe , Anya Golder , Samantha Littler
Nature Communications 11 ( 1) 822 -822

55
2020
Non-random Mis-segregation of Human Chromosomes.

Joseph Thomas Worrall , Naoka Tamura , Alice Mazzagatti , Nadeem Shaikh
Cell Reports 23 ( 11) 3366 -3380

40
2018
The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α

Susana Simões-Sousa , Samantha Littler , Sarah L. Thompson , Paul Minshall
Cell Reports 25 ( 3) 749 -760

15
2018
Extensive Clonal Branching Shapes the Evolutionary History of High-Risk Pediatric Cancers

Natalie Andersson , Bjorn Bakker , Jenny Karlsson , Anders Valind
Cancer Research 80 ( 7) 1512 -1523

4
2020
Aneuploidy in stem cells.

Jorge Garcia-Martinez , Bjorn Bakker , Klaske M Schukken , Judith E Simon
World Journal of Stem Cells 8 ( 6) 216 -222

6
2016
Nuclear chromosome locations dictate segregation error frequencies

Sjoerd J Klaasen , My Anh Truong , Richard H van Jaarsveld , Isabella Koprivec
Nature 607 ( 7919) 604 -609

8
2022
Targeted cancer therapy induces APOBEC fueling the evolution of drug resistance

Manasi Mayekar , Deborah Caswell , Natalie Vokes , Emily K Law
Cancer Research 82 ( 12\_Supplement) 2197 -2197

12
2022
Lung adenocarcinoma promotion by air pollutants

William Hill , Emilia L Lim , Clare E Weeden , Claudia Lee
Nature 616 ( 7955) 159 -167

211
2023
The H3. 3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma

Irena Bočkaj , Tosca EI Martini , Eduardo S de Camargo Magalhães , Petra L Bakker
PLoS genetics 17 ( 11) e1009868 -e1009868

16
2021
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain

Esther Stroo , Leen Janssen , Olga Sin , Wytse Hogewerf
Life science alliance 6 ( 7)

2
2023
The impact of monosomies, trisomies and segmental aneuploidies on chromosomal stability

Dorine C Hintzen , Mar Soto , Michael Schubert , Bjorn Bakker
PLoS One 17 ( 7) e0268579 -e0268579

9
2022
Monosomies, trisomies and segmental aneuploidies differentially affect chromosomal stability

Dorine C Hintzen , Mar Soto , Michael Schubert , Bjorn Bakker
BioRxiv 2021.08. 31.458318 -2021.08. 31.458318

7
2021
Cancer tolerance to chromosomal instability is driven by Stat1 inactivation in vivo

Michael Schubert , Christy Hong , Laura J Jilderda , Marta Requesens Rueda
BioRxiv 2021.12. 03.471107 -2021.12. 03.471107

8
2021
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance

Deborah R Caswell , Philippe Gui , Manasi K Mayekar , Emily K Law
Nature Genetics 56 ( 1) 60 -73

13
2024
The role of APOBEC3B in lung tumour evolution and targeted therapy resistance

Deborah R Caswell , Manasi K Mayekar , Philippe Gui , Emily K Law
bioRxiv 2020.12. 18.423280 -2020.12. 18.423280

2
2020
TP53 loss with whole genome doubling mediates heterogeneous intra-patient therapy response in EGFR-driven lung adenocarcinoma: A TRACERx study

Sebastijan Hobor , Maise Al Bakir , Marcin Skrzypski , Alexander M Frankell
Cancer Research 82 ( 12_Supplement) 6217 -6217

2022
BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome

Cynthia J Sieben , Karthik B Jeganathan , Grace G Nelson , Ines Sturmlechner
The Journal of clinical investigation 130 ( 1) 171 -188

17
2020
Quantification of aneuploidy in mammalian systems

Hilda van den Bos , Bjorn Bakker , Aaron Taudt , Victor Guryev
Cellular Senescence: Methods and Protocols 159 -190

46
2019
Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum

Irena Bočkaj , Tosca EI Martini , Marlinde J Smit , Inna Armandari
International Journal of Molecular Sciences 23 ( 17) 9852 -9852

2
2022
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling

Sebastijan Hobor , Maise Al Bakir , Crispin T Hiley , Marcin Skrzypski
Nature Communications 15 ( 1) 4871 -4871

2024