Regulation of Lymphocyte Function by Adenosine

JoelLinden , CaglarCekic
Arteriosclerosis, Thrombosis, and Vascular Biology

2012
Methods and compositions for treating cancer

George A Gaitanaris , Marc A Gavin , Robert H Lemus , Caglar Cekic

2023
Adenosine A2B receptor blockade slows growth of bladder and breast tumors

Caglar Cekic , Duygu Sag , Yuesheng Li , Dan Theodorescu
The FASEB Journal 26

2012
Interleukin-7 protects CD8+ T cells from adenosine-mediated immunosuppression

Caglar Cekic , Caglar Cekic , Merve Kayhan , Ali Can Savas
Science Signaling 14 ( 674)

10
2021
Targeting adenosine with adenosine deaminase 2 to inhibit growth of solid tumors

Lin Wang , Luz M Londono , Jessica Cowell , Ozge Saatci
Cancer Research

2021
Ecto-5'-Nucleotidase (CD73) Regulates the Survival of CD8+ T Cells.

Mario Rosemblatt , Mario Rosemblatt , Álvaro Lladser , Daniela Sauma
Frontiers in Cell and Developmental Biology 9 647058 -647058

2021
Adenosine Receptor Signaling Targets Both PKA and Epac Pathways to Polarize Dendritic Cells to a Suppressive Phenotype.

Merve Kayhan , Altay Koyas , Imran Akdemir , Ali Can Savas
Journal of Immunology 203 ( 12) 3247 -3255

8
2019
The Expression of Adenosine A2B Receptor on Antigen Presenting Cells Suppresses CD8+ T cell Responses and Promotes Tumor Growth

Siqi Chen , Imran Akdemir , Jie Fan , Joel Linden
Cancer immunology research 8 ( 8) 1064 -1074

6
2020
Purinergic regulation of the immune system

Caglar Cekic , Joel Linden
Nature Reviews Immunology 16 ( 3) 177 -192

659
2016
The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity

Duygu Sag , Caglar Cekic , Runpei Wu , Joel Linden
Nature Communications 6 ( 1) 6354 -6354

66
2015
IFN-β Production by TLR4-Stimulated Innate Immune Cells Is Negatively Regulated by GSK3-β

Huizhi Wang , Carlos A. Garcia , Kunal Rehani , Caglar Cekic
Journal of Immunology 181 ( 10) 6797 -6802

72
2008
Extracellular adenosine regulates naive T cell development and peripheral maintenance.

Caglar Cekic , Duygu Sag , Yuan-Ji Day , Joel Linden
Journal of Experimental Medicine 210 ( 12) 2693 -2706

59
2013
Adenosine A2A Receptors Intrinsically Regulate CD8+ T Cells in the Tumor Microenvironment

Caglar Cekic , Joel Linden
Cancer Research 74 ( 24) 7239 -7249

78
2014
Myeloid Expression of Adenosine A2A Receptor Suppresses T and NK Cell Responses in the Solid Tumor Microenvironment

Caglar Cekic , Yuan-Ji Day , Duygu Sag , Joel Linden
Cancer Research 74 ( 24) 7250 -7259

127
2014
Selective activation of the p38 MAPK pathway by synthetic monophosphoryl lipid A.

Caglar Cekic , Carolyn R. Casella , Chelsea A. Eaves , Atsushi Matsuzawa
Journal of Biological Chemistry 284 ( 46) 31982 -31991

70
2009
MyD88-Dependent SHIP1 Regulates Proinflammatory Signaling Pathways in Dendritic Cells after Monophosphoryl Lipid A Stimulation of TLR4

Caglar Cekic , Carolyn R. Casella , Duygu Sag , Frann Antignano
Journal of Immunology 186 ( 7) 3858 -3865

30
2011
Modulation of myeloid cells by adenosine signaling.

Caglar Cekic
Current Opinion in Pharmacology 53 134 -145

1
2020
Reactivation of cAMP Pathway by PDE4D Inhibition Represents a Novel Druggable Axis for Overcoming Tamoxifen Resistance in ER-positive Breast Cancer

Rasmi R Mishra , Nevin Belder , Suhail A Ansari , Merve Kayhan
Clinical Cancer Research 24 ( 8) 1987 -2001

13
2018
Structure-function studies on low-toxicity TLR4 simulation

Caglar Cekic
University of Louisville

2010
Patrolling monocytes control tumor metastasis to the lung

R. N. Hanna , C. Cekic , D. Sag , R. Tacke
Science 350 ( 6263) 985 -990

218
2015