Requirement for Interaction of PI3-Kinase p110α with RAS in Lung Tumor Maintenance

Esther Castellano , Clare Sheridan , May Zaw Thin , Emma Nye
Cancer Cell 24 ( 5) 617 -630

118
2013
Dual Regulation of Fbw7 Function and Oncogenic Transformation by Usp28

Christina Schülein-Völk , Elmar Wolf , Jing Zhu , Wenshan Xu
Cell Reports 9 ( 3) 1099 -1109

55
2014
Arginine methylation of the c‐Jun coactivator RACO‐1 is required for c‐Jun/AP‐1 activation

Clare C Davies , Atanu Chakraborty , Markus E Diefenbacher , Mark Skehel
The EMBO Journal 32 ( 11) 1556 -1567

22
2013
Maintaining protein stability of∆ Np63 via USP 28 is required by squamous cancer cells

Cristian Prieto‐Garcia , Oliver Hartmann , Michaela Reissland , Fabian Braun
EMBO Molecular Medicine 12 ( 4) e11101

31
2020
USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer

Carina R Maier , Oliver Hartmann , Cristian Prieto-Garcia , Kamal M Al-Shami
Cell Death & Differentiation 30 ( 7) 1710 -1725

3
2023
Stabilisation of β-Catenin-WNT signalling by USP10 in APC-truncated colorectal cancer drives cancer stemness and enables super-competitor signalling

Michaela Reissland , Oliver Hartmann , Saskia Tauch , Cristian Prieto-Garcia
bioRxiv 2023.02. 10.527983 -2023.02. 10.527983

1
2023
RNA polymerase I inhibition induces terminal differentiation, growth arrest, and vulnerability to senolytics in colorectal cancer cells

Christoph Otto , Carolin Kastner , Stefanie Schmidt , Konstantin Uttinger
Molecular Oncology 16 ( 15) 2788 -2809

1
2022
Maintaining protein stability of∆ Np63 via USP28 is required by squamous cancer cells

Christian Münch11 Maric10 , Mathias Rosenfeldt , Martin Eilers , Markus E Diefenbacher

DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma

Alexander Strubel , Philipp Münick , Oliver Hartmann , Apirat Chaikuad
Cell Death & Disease 14 ( 10) 674 -674

1
2023
USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K

Cristian Prieto‐Garcia , Oliver Hartmann , Michaela Reissland , Fabian Braun
Molecular Oncology 16 ( 17) 3082 -3106

6
2022
Myosin Va cooperates with PKA RIαto mediate maintenance of the endplate in vivo

Kyeong-Rock Choi , Markus Reischl , Yvonne Petersen , Markus E Diefenbacher
Proceedings of the National Academy of Sciences of the United States of America 107 ( 5)

2010
PTEN mutant non-small cell lung cancer require ATM to suppress pro-apoptotic signalling and evade radiotherapy

Thomas Fischer , Oliver Hartmann , Michaela Reissland , Cristian Prieto-Garcia
Cell & Bioscience 12 ( 1) 50 -50

14
2022
Inhibition of USP28 overcomes Cisplatin-resistance of squamous tumors by suppression of the Fanconi anemia pathway

Cristian Prieto-Garcia , Oliver Hartmann , Michaela Reissland , Thomas Fischer
Cell Death & Differentiation 29 ( 3) 568 -584

20
2022
Metabolism‐focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer

Takashi Furusawa , Renzo Cavero , Yue Liu , Haojian Li
Molecular Carcinogenesis 63 ( 6) 1024 -1037

2024
PTEN mutant NSCLC require ATM to suppress pro-apoptotic signalling and evade radiotherapy

Thomas Fischer , Oliver Hartmann , Michaela Reissland , Cristian Prieto-Garcia
bioRxiv 2021.07. 24.453632 -2021.07. 24.453632

2021
LUBAC determines chemotherapy resistance in squamous cell lung cancer.

E Josue Ruiz , Markus E Diefenbacher , Jessica K Nelson , Rocio Sancho
Journal of Experimental Medicine 216 ( 2) 450 -465

25
2019
Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease.

Oliver Hartmann , Michaela Reissland , Carina R Maier , Thomas Fischer
Frontiers in Cell and Developmental Biology 9 641618 -641618

2021
The USP28-ΔNp63 axis is a vulnerability of squamous tumours

Cristian Prieto-Garcia , Oliver Hartmann , Michaela Reissland , Fabian Braun
bioRxiv 683508

2019
Autophagy blockage reduces the incidence of pancreatic ductal adenocarcinoma in the context of mutant Trp53

Laura Mainz , Mohamed AFE Sarhan , Sabine Roth , Ursula Sauer
Frontiers in Cell and Developmental Biology 10 785252 -785252

2
2022
USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer

Michaela Reissland , Oliver Hartmann , Saskia Tauch , Jeroen M Bugter
Oncogene 1 -15

2024