Cyclic dinucleotides as agonists of stimulator of interferon gene dependent signalling

Maria Emilia Di Francesco , Philip Jones , Michael A. Curran

4
2018
Development of Immunotherapy Combination Strategies in Cancer

Hussein A. Tawbi , Justin T. Moyers , Timothy A. Yap , Michael A. Curran
Cancer Discovery 11 ( 6) 1368 -1397

1
2021
Prolonged transgene expression in murine salivary glands following non-primate lentiviral vector transduction

Ela Shai , Aaron Palmon , Amos Panet , Yitzhak Marmary
Molecular Therapy 12 ( 1) 137 -143

16
2005
Intratumoral STING activation with T cell checkpoint modulation generates systemic antitumor immunity

Casey R. Ager , Matthew J. Reilley , Courtney Nicholas , Todd Bartkowiak
Cancer immunology research 5 ( 8) 676 -684

69
2017
Melanoma evolves complete immunotherapy resistance through the acquisition of a hypermetabolic phenotype

Ashvin R. Jaiswal , Arthur J. Liu , Shivanand Pudakalakatti , Prasanta Dutta
Cancer immunology research 8 ( 11) 1365 -1380

4
2020
28
2012
Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy.

Casey R. Ager , Huaping Zhang , Zhanlei Wei , Philip Jones
Bioorganic & Medicinal Chemistry Letters 29 ( 20) 126640

21
2019
Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy

Priyamvada Jayaprakash , Midan Ai , Arthur Liu , Pratha Budhani
Journal of Clinical Investigation 128 ( 11) 5137 -5149

236
2018
Abstract IA11: Reversal of immunotherapy resistance through hypoxia reduction

Priyamvada Jayaprakash , Midan Ai , Michael A. Curran
Clinical Cancer Research 26

1
2020
Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration

Martina Ott , Karl-Heinz Tomaszowski , Anantha Marisetty , Ling-Yuan Kong
JCI Insight 5 ( 17)

2
2020
Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype.

Konrad Gabrusiewicz , Benjamin Rodriguez , Jun Wei , Yuuri Hashimoto
JCI insight 1 ( 2)

338
2016
Peripheral and tumor immune correlates in patients with advanced melanoma treated with combination nivolumab (anti-PD-1, BMS-936558, ONO-4538) and ipilimumab.

Margaret K. Callahan , Christine E. Horak , Michael A. Curran , Travis Hollman
Journal of Clinical Oncology 31 3003 -3003

36
2013
Tumor vaccines expressing flt3 ligand synergize with ctla-4 blockade to reject preimplanted tumors.

Michael A. Curran , James P. Allison
Cancer Research 69 ( 19) 7747 -7755

113
2009
Retrovirally transferred genes inhibit apoptosis in an insulin-secreting cell line: implications for islet transplantation.

Elizabeth S. Fenjves , M. Sofia Ochoa , Carlota Gay-Rabinstein , Camillo Ricordi
Cell Transplantation 13 ( 5) 489 -496

8
2004
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma

Stephen M.F. Jamieson , Peter Tsai , Maria K. Kondratyev , Pratha Budhani
JCI insight 3 ( 16)

51
2018
Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression.

Qingsong Hu , Youqiong Ye , Li-Chuan Chan , Yajuan Li
Nature Immunology 20 ( 7) 835 -851

214
2019
EnanDIM - a novel family of L-nucleotide-protected TLR9 agonists for cancer immunotherapy

Kerstin Kapp , Barbara Volz , Michael A. Curran , Detlef Oswald
Journal for ImmunoTherapy of Cancer 7 ( 1) 5

2
2019
Targeting interferon signaling and CTLA-4 enhance the therapeutic efficacy of anti-PD-1 immunotherapy in preclinical model of HPV + oral cancer

Stephanie Dorta-Estremera , Venkatesh L. Hegde , Ravaen B. Slay , Rachel Sun
Journal for ImmunoTherapy of Cancer 7 ( 1) 252 -252

41
2019
TLR9 activation cooperates with T cell checkpoint blockade to regress poorly immunogenic melanoma

Matthew J. Reilley , Brittany Morrow , Casey R. Ager , Arthur Liu
Journal for ImmunoTherapy of Cancer 7 ( 1) 323

13
2019
Systemic 4-1BB activation induces a novel T cell phenotype driven by high expression of Eomesodermin

Michael A. Curran , Theresa L. Geiger , Welby Montalvo , Myoungjoo Kim
Journal of Experimental Medicine 210 ( 4) 743 -755

122
2013