Helena D. Janse van Rensburg
机构: Centre of Excellence for Pharmaceutical Sciences, North-West University
每年引用次数
引用次数
引用: 115
H-指数: 7
I10-指数 : 4
出版物: 27
5-Substituted 2-benzylidene-1-tetralone analogues as A 1 and/or A 2A antagonists for the potential treatment of neurological conditions
H.D. Janse van Rensburg , G. Terre'Blanche , M.M. van der Walt , L.J. Legoabe
Bioorganic Chemistry 74 251 -259
7
2017
Synthesis and Structure Activity Relationships of Chalcone based Benzocycloalkanone Derivatives as Adenosine A1 and/or A2A Receptor Antagonists.
Helena D. Janse van Rensburg , Lesetja J. Legoabe , Gisella Terre’Blanche
Drug Research 70 ( 06) 243 -256
2020
Synthesis and evaluation of methoxy substituted 2-benzoyl-1-benzofuran derivatives as lead compounds for the development adenosine A1 and/or A2A receptor antagonists.
Helena D. Janse van Rensburg , Lesetja J. Legoabe , Gisella Terre'Blanche , Janine Aucamp
Bioorganic Chemistry 94 103459
3
2020
C3 amino-substituted chalcone derivative with selective adenosine rA1 receptor affinity in the micromolar range.
Helena D. Janse van Rensburg , Lesetja J. Legoabe , Gisella Terre’Blanche
Chemical Papers 75 ( 4) 1 -25
2021
Methoxy substituted 2-benzylidene-1-indanone derivatives as A1 and/or A2A AR antagonists for the potential treatment of neurological conditions
Helena D. Janse van Rensburg , Lesetja J. Legoabe , Gisella Terre'Blanche , Mietha M. Van der Walt
MedChemComm 10 ( 2) 300 -309
5
2019
2-Benzylidene-1-Indanone Analogues as Dual Adenosine A1/A2a Receptor Antagonists for the Potential Treatment of Neurological Conditions.
HelenaDorathea Janse van Rensburg , LesetjaJ. Legoabe , Gisella Terre’Blanche , MiethaM. Van der Walt
Drug Research 69 ( 07) 382 -391
6
2019
Preliminary Screening of South African Plants for Binding Affinity to the Serotonin Reuptake Transporter and Adenosine A1/A2A Receptors
Andisiwe Mnqika , Adeyemi O Aremu , HD Janse van Rensburg , Makhotso Lekhooa
Scientia Pharmaceutica 91 ( 3) 41 -41
2023
Synthesis and evaluation of chalcones and structurally related compounds as adenosine A₁ and/or A₂ᴀ receptor antagonists for the potential treatment of neurological conditions
HD Janse van Rensburg
North-West University (South-Africa)
2021
Exploration of ethylene glycol linked nitrofurantoin derivatives against Leishmania: Synthesis and in vitro activity
Keitumetsi Ndlovu , Christina Kannigadu , Janine Aucamp , Helena D Janse Van Rensburg
Archiv der Pharmazie 356 ( 5) 2200529 -2200529
1
2023
Prophylactic activity of orally administered dry-heat-sterilized Acremonium egyptiacum against Trypanosoma congolense-induced animal African trypanosomosis
Ai Yamazaki , Yusuke Tanaka , Kenichi Watanabe , Mayu Sato
Acta Tropica 254 107185 -107185
2024
In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives
Helena D Janse van Rensburg , DN'Da David , Keisuke Suganuma ,
European Journal of Pharmaceutical Sciences 192 106668 -106668
2024
In Vitro and In Vivo Trypanocidal Efficacy of Nitrofuryl-and Nitrothienylazines
Helena D Janse van Rensburg , David D N’Da , Keisuke Suganuma
ACS omega 8 ( 45) 43088 -43098
2023
In vitro trypanocidal activities and structure–activity relationships of ciprofloxacin analogs
Helena D Janse van Rensburg , Keisuke Suganuma , David D N’Da
Molecular Diversity 1 -14
2023
In Vitro and in Vivo Trypanocidal Efficacy of Ethylene Glycol Linked Nitrofurantoin Derivatives
Helena D Janse van Rensburg , David N'Da , Keisuke Suganuma
Available at SSRN 4513604
Design, synthesis, electrochemistry and anti-trypanosomatid hit/lead identification of nitrofuranylazines
Maryna Saayman , Christina Kannigadu , Janine Aucamp , Helena D Janse van Rensburg
RSC Medicinal Chemistry 14 ( 10) 2012 -2029
2
2023
Synthesis and in vitro antileishmanial activity of alkylene-linked nitrofurantoin-triazole hybrids
Nonkululeko H Zuma , Janine Aucamp , Helena D Janse van Rensburg , DN'Da David
European Journal of Medicinal Chemistry 246 115012 -115012
8
2023
Probing benzothiadiazine-1, 1-dioxide ethylene glycol derivatives against Leishmania: synthesis and in vitro efficacy evaluation
Nadine Henning , Christina Kannigadu , Janine Aucamp , Helena D Janse van Rensburg
2023
Exploration of chalcones and related heterocycle compounds as ligands of adenosine receptors: therapeutics development
Chrisna Matthee , Gisella Terre’Blanche , Lesetja J Legoabe , Helena D Janse van Rensburg
Molecular Diversity 1 -43
7
2022
Design, synthesis and evaluation of amino-3, 5-dicyanopyridines and thieno [2, 3-b] pyridines as ligands of adenosine A1 receptors for the potential treatment of epilepsy
Gaofenngwe Nkomba , Gisella Terre’Blanche , Helena D Janse van Rensburg , Lesetja J Legoabe
Medicinal Chemistry Research 31 ( 8) 1277 -1297
5
2022
Chalcone‐inspired r A1/A2A adenosine receptor ligands: Ring closure as an alternative to a reactive substructure
Chrisna Matthee , Gisella Terre’Blanche , Helena D Janse van Rensburg , Janine Aucamp
Chemical Biology & Drug Design 99 ( 3) 416 -437
5
2022