Molecular targeted therapy of lung cancer: EGFR mutations and response to EGFR inhibitors.

D.A. HABER , D.W. BELL , R. SORDELLA , E.L. KWAK
Cold Spring Harbor Symposia on Quantitative Biology 70 419 -426

138
2005
Method for treating gefitinib resistant cancer

Sridhar Krishna Rabindran , Raffaella Sordella , Daniel A. Haber , Jeffrey E. Settleman

36
2006
Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments

Raffaella Sordella , Daniel A. Haber , Jeffrey E. Settleman , Bruce E. Johnson

148
2005
The Evolution of TP53 Mutations: From Loss-of-Function to Separation-of-Function Mutants

Raffaella Sordella , Debjani Pal , Nitin Shirole , Madison Miller
Journal of cancer biology & research 4 ( 4)

6
2016
DOCK4, a GTPase activator, is disrupted during tumorigenesis.

Vijay Yajnik , Charles Paulding , Raffaella Sordella , Andrea I. McClatchey
Cell 112 ( 5) 673 -684

201
2003
Modulation of Rho GTPase Signaling Regulates a Switch between Adipogenesis and Myogenesis

Raffaella Sordella , Wei Jiang , Guang-Chao Chen , Marcello Curto
Cell 113 ( 2) 147 -158

456
2003
Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR

Daphne W Bell , Ira Gore , Ross A Okimoto , Nadia Godin-Heymann
Nature Genetics 37 ( 12) 1315 -1316

579
2005
Towards patient-based cancer therapeutics

Cancer Target Discovery and Development Network , Stuart L Schreiber , Alykhan F Shamji , Paul A Clemons
Nature Biotechnology 28 ( 9) 904 -906

69
2010
Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752

Gromoslaw A. Smolen , Raffaella Sordella , Beth Muir , Gayatry Mohapatra
Proceedings of the National Academy of Sciences of the United States of America 103 ( 7) 2316 -2321

454
2006
A rapid and scalable system for studying gene function in mice using conditional RNA interference.

Prem K. Premsrirut , Lukas E. Dow , Sang Yong Kim , Matthew Camiolo
Cell 145 ( 1) 145 -158

238
2011
Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development

Raffaella Sordella , Marie Classon , Kang-Quan Hu , Stephen F. Matheson
Developmental Cell 2 ( 5) 553 -565

119
2002
Dialogue between RhoA/ROCK and Members of the Par Complex in Cell Polarity

Raffaella Sordella , Linda Van Aelst
Developmental Cell 14 ( 2) 150 -152

8
2008
MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2

Dawid G. Nowak , Hyejin Cho , Tali Herzka , Kaitlin Watrud
Cancer Discovery 5 ( 6) 636 -651

37
2015
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

Thomas J. Lynch , Daphne W. Bell , Raffaella Sordella , Sarada Gurubhagavatula
The New England Journal of Medicine 350 ( 21) 2129 -2139

13,399
2004
Increased Prevalence of EGFR-Mutant Lung Cancer in Women and in East Asian Populations: Analysis of Estrogen-Related Polymorphisms

Daphne W. Bell , Brian W. Brannigan , Keitaro Matsuo , Dianne M. Finkelstein
Clinical Cancer Research 14 ( 13) 4079 -4084

56
2008
Metabolic Alterations in Lung Cancer–Associated Fibroblasts Correlated with Increased Glycolytic Metabolism of the Tumor

Virendra K. Chaudhri , Gregory G. Salzler , Salihah A. Dick , Melanie S. Buckman
Molecular Cancer Research 11 ( 6) 579 -592

60
2013
Epidermal Growth Factor Receptor Mutants from Human Lung Cancers Exhibit Enhanced Catalytic Activity and Increased Sensitivity to Gefitinib

Roseann Mulloy , Audrey Ferrand , Youngjoo Kim , Raffaella Sordella
Cancer Research 67 ( 5) 2325 -2330

169
2007
Distinct but overlapping functions for the closely related p190 RhoGAPs in neural development.

Stephen F. Matheson , Kang-Quan Hu , Madeleine R. Brouns , Raffaella Sordella
Developmental Neuroscience 28 ( 6) 538 -550

24
2006