引用次数
引用: 15,924
H-指数: 29
I10-指数 : 36
出版物: 57
Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia.
Arthur B. Raitano , James Kuo , Douglas C. Saffran , Daniel E. H. Afar
Cancer Research 61 ( 4) 1686 -1692
283
2001
Mathematical modeling identifies optimum lapatinib dosing schedules for the treatment of glioblastoma patients.
Shayna Stein , Rui Zhao , Hiroshi Haeno , Igor Vivanco
PLOS Computational Biology 14 ( 1)
25
2018
Epidermal growth factor receptor inhibitors in oncology
Igor Vivanco , Ingo K Mellinghoff
Current Opinion in Oncology 22 ( 6) 573 -578
53
2010
Identification of an androgen-dependent enhancer within the prostate stem cell antigen gene.
Anjali Jain , Amanda Lam , Igor Vivanco , Michael F. Carey
Molecular Endocrinology 16 ( 10) 2323 -2337
48
2002
Abstract CT140: Proof-of-concept evidence of immune modulation by blockade of the phosphatidylinositol 3-kinase (PI3K)-AKT signaling pathway in the phase I dose escalation study of Ipatasertib (Ipa) in combination with atezolizumab (A) in patients (pts) with advanced solid tumors (Ice-CAP)
Juanita S. Lopez , Andrea Biondo , Crescens Tiu , Mariana Scaranti
Cancer Research 80
2020
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
Igor Vivanco , Charles L. Sawyers
Nature Reviews Cancer 2 ( 7) 489 -501
7,404
2002
RBTT-06. TESSA JOWELL BRAIN MATRIX STUDY: A BRITISH FEASIBILITY STUDY OF MOLECULAR STRATIFICATION AND TARGETED THERAPY TO OPTIMIZE THE CLINICAL MANAGEMENT OF PATIENTS WITH GLIOMA
Colin Watts , John Apps , Olaf Ansorg , Josh Savage
Neuro-oncology 21
1
2019
SCIDOT-08. CHILDREN’S BRAIN TUMOUR DRUG DELIVERY CONSORTIUM (CBTDDC)
Ruman Rahman , Emma Campbell , Henry Brem , Monica Pearl
Neuro-oncology 21
2019
Differential Sensitivity of Glioma- versus Lung Cancer–Specific EGFR Mutations to EGFR Kinase Inhibitors
Igor Vivanco , H. Ian Robins , Daniel Rohle , Carl Campos
Cancer Discovery 2 ( 5) 458 -471
329
2012
A kinase-independent function of AKT promotes cancer cell survival
Igor Vivanco , Zhi C Chen , Barbara Tanos , Barbara Oldrini
eLife 3
81
2014
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.
Ingo K Mellinghoff , Maria Y Wang , Igor Vivanco , Daphne A Haas-Kogan
The New England Journal of Medicine 353 ( 19) 2012 -2024
1,680
2005
Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies
Selvaraju Veeriah , Barry S Taylor , Shasha Meng , Fang Fang
Nature Genetics 42 ( 1) 77 -82
381
2010
Murine Cell Lines Derived from Pten Null Prostate Cancer Show the Critical Role of PTEN in Hormone Refractory Prostate Cancer Development
Jing Jiao , Shunyou Wang , Rong Qiao , Igor Vivanco
Cancer Research 67 ( 13) 6083 -6091
202
2007
A systematic molecular and pharmacologic evaluation of AKT inhibitors reveals new insight into their biological activity.
Eleftherios Kostaras , Teresa Kaserer , Glorianne Lazaro , Sara Farrah Heuss
British Journal of Cancer 123 ( 4) 542 -555
5
2020
Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer
Lucia Regales , Yixuan Gong , Ronglai Shen , Elisa de Stanchina
Journal of Clinical Investigation 119 ( 10) 3000 -3010
324
2009
EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer.
Barbara Oldrini , Wan-Ying Hsieh , Hediye Erdjument-Bromage , Paolo Codega
Nature Communications 8 ( 1) 2035 -2035
13
2017
Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death
Nicholas A Graham , Martik Tahmasian , Bitika Kohli , Evangelia Komisopoulou
Molecular Systems Biology 8 ( 1) 589 -589
204
2012
Inhibitors in AKTion: ATP-competitive vs allosteric.
Glorianne Lazaro , Eleftherios Kostaras , Igor Vivanco
Biochemical Society Transactions 48 ( 3) 933 -943
21
2020
14-3-3σ and p21 synergize to determine DNA damage response following Chk2 inhibition
Shasha Meng , Tali Arbit , Selvaraju Veeriah , Ingo K. Mellinghoff
Cell Cycle 8 ( 14) 2238 -2246
9
2009
Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma
Evon Poon , Tong Liang , Yann Jamin , Susanne Walz
Journal of Clinical Investigation 130 ( 11) 5875 -5892
2
2020