作者: Igor Vivanco , Ingo K Mellinghoff
DOI: 10.1097/CCO.0B013E32833EDBDF
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摘要: Purpose of reviewInhibition the epidermal growth factor receptor (EGFR) by small molecules or antibodies has been pursued as a paradigm to treat human cancers for over two decades. It is now clear that these agents can induce tumor regressions in variety cancers, proving critical r