Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases
Haitao Yang , Weiqing Xie , Xiaoyu Xue , Kailin Yang
PLOS Biology 3 ( 10) 324 -334
343
2005
Rational library design by functional CDR resampling.
Qi Zhao , Diane Buhr , Courtney Gunter , Jenny Frenette
New Biotechnology 45 89 -97
2
2018
A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro.
Deping Wang , Cheng Chen , Shengnan Liu , Han Zhou
Scientific Reports 7 ( 1) 42580 -42580
16
2017
Recent Developments on Coronavirus Main Protease/3C Like Protease Inhibitors
Qi Zhao , Erin Weber , Haitao Yang
Recent Patents on Anti-infective Drug Discovery 8 ( 2) 150 -156
23
2013
Production of authentic SARS-CoV M(pro) with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction.
Xiaoyu Xue , Haitao Yang , Wei Shen , Qi Zhao
Journal of Molecular Biology 366 ( 3) 965 -975
123
2007
Michael Acceptor-Based Peptidomimetic Inhibitor of Main Protease from Porcine Epidemic Diarrhea Virus
Fenghua Wang , Cheng Chen , Kailin Yang , Yang Xu
Journal of Medicinal Chemistry 60 ( 7) 3212 -3216
25
2017
New nsp8 isoform suggests mechanism for tuning viral RNA synthesis
Shuang Li , Qi Zhao , Yinjie Zhang , Yang Zhang
Protein & Cell 1 ( 2) 198 -204
13
2010
Structural basis of Zika virus helicase in recognizing its substrates
Hongliang Tian , Xiaoyun Ji , Xiaoyun Yang , Zhongxin Zhang
Protein & Cell 7 ( 8) 562 -570
45
2016
Mechanism of Dephosphorylation of Glucosyl-3-phosphoglycerate by a Histidine Phosphatase
Qianqian Zheng , Dunquan Jiang , Wei Zhang , Qingqing Zhang
Journal of Biological Chemistry 289 ( 31) 21242 -21251
7
2014
Mechanism of ATP hydrolysis by the Zika virus helicase.
Xiaoyun Yang , Cheng Chen , Hongliang Tian , Heng Chi
The FASEB Journal 32 ( 10) 5250 -5257
6
2018
Crystallization and preliminary crystallographic study of human coronavirus NL63 main protease in complex with an inhibitor.
Fenghua Wang , Yusheng Tan , Huiyan Li , Xia Chen
Acta Crystallographica Section F-structural Biology and Crystallization Communications 70 ( 8) 1068 -1071
1
2014
Crystallization and preliminary crystallographic study of Feline infectious peritonitis virus main protease in complex with an inhibitor
Jinshan Wang , Fenghua Wang , Yusheng Tan , Xia Chen
Acta Crystallographica Section F-structural Biology and Crystallization Communications 70 ( 12) 1612 -1615
1
2014
Expression, crystallization and preliminary crystallographic study of the functional mutant (N60K) of nonstructural protein 9 from Human coronavirus HKU1.
Xia Chen , Yusheng Tan , Fenghua Wang , Jinshan Wang
Acta Crystallographica Section F-structural Biology and Crystallization Communications 70 ( 12) 1620 -1623
2014
Crystallization and preliminary crystallographic study of Porcine epidemic diarrhea virus main protease in complex with an inhibitor
Yusheng Tan , Fenghua Wang , Xia Chen , Jinshan Wang
Acta Crystallographica Section F-structural Biology and Crystallization Communications 70 ( 12) 1608 -1611
2014
Structural insights into 5′ flap DNA unwinding and incision by the human FAN1 dimer
Qi Zhao , Xiaoyu Xue , Simonne Longerich , Patrick Sung
Nature Communications 5 ( 1) 5726 -5726
18
2014
Purification, crystallization and preliminary crystallographic analysis of avian infectious bronchitis virus nsp3 ADRP domain.
Lei Wei , Cheng Chen , Qi Zhao , Chun Li
Acta Crystallographica Section F-structural Biology and Crystallization Communications 64 ( 9) 802 -804
2
2008
Crystal structures of two coronavirus ADP-ribose-1″-monophosphatases and their complexes with ADP-ribose: a systematic structural analysis of the viral ADRP domain.
Yuanyuan Xu , Le Cong , Cheng Chen , Lei Wei
Journal of Virology 83 ( 2) 1083 -1092
48
2009
Study of Mendelian forms of Crohn's disease in Saudi Arabia reveals novel risk loci and alleles
Nisha Patel , Mohammad I El Mouzan , Sulaiman M Al-Mayouf , Nouran Adly
Gut 63 ( 11) 1831 -1832
31
2014
Structures of Two Coronavirus Main Proteases : Implications for Substrate Binding and Antiviral Drug Design
Xiaoyu Xue , Hongwei Yu , Haitao Yang , Fei Xue
Journal of Virology 82 ( 5) 2515 -2527
403
2008
HIV suppression by host restriction factors and viral immune evasion
Xiaofei Jia , Qi Zhao , Yong Xiong
Current Opinion in Structural Biology 31 106 -114
29
2015