Vascular Endothelial ACE Deletion does not Prevent 20-HETE-dependent Vascular Remodeling
John Falck , Kenneth Bernstein , Brian Shkolnik , Victor Garcia
The FASEB Journal 29
2015
20-SOLA, a Novel Water Soluble 20-HETE Antagonist, Reduces Blood Pressure Through Regulation of Vascular ACE Expression via an IKK Dependent Pathway
John Falck , Brian Shkolnik , Victor Garcia , Michal Schwartzman
The FASEB Journal 29
2
2015
Unraveling the Role of 12- and 20- HETE in Cardiac Pathophysiology: G-Protein-Coupled Receptors, Pharmacological Inhibitors, and Transgenic Approaches.
Victor Garcia , Jonathan V. Pascale , Pamela A. Lucchesi
Journal of Cardiovascular Pharmacology 77 ( 6) 707 -717
2021
Uncovering the signaling, structure and function of the 20‐HETE‐GPR75 pairing: Identifying CCL5 as a negative regulator of GPR75
John R. Falck , Victor Garcia , Michal Laniado Schwartzman , Eon Joo Park
British Journal of Pharmacology
2021
Androgen-Sensitive Hypertension Associates with Upregulated Vascular CYP4A12–20-HETE Synthase
Cheng-Chia Wu , Shaojun Mei , Jennifer Cheng , Yan Ding
Journal of The American Society of Nephrology 24 ( 8) 1288 -1296
40
2013
Hypertension Is a Major Contributor to 20-Hydroxyeicosatetraenoic Acid–Mediated Kidney Injury in Diabetic Nephropathy
Mahesha H. Gangadhariah , James M. Luther , Victor Garcia , Paisit Paueksakon
Journal of the American Society of Nephrology 26 ( 3) 597 -610
27
2015
19-Hydroxyeicosatetraenoic acid analogs: Antagonism of 20-hydroxyeicosatetraenoic acid-induced vascular sensitization and hypertension.
Rambabu Dakarapu , Ramu Errabelli , Vijaya L. Manthati , Adeniyi Michael Adebesin
Bioorganic & Medicinal Chemistry Letters 29 ( 19) 126616 -126616
3
2019
Androgen-sensitive hypertension associated with soluble guanylate cyclase alpha1 deficiency is mediated by 20-HETE
Sara Vandenwijngaert , Ana C Dordea , Victor Garcia , Robert E Tainsh
BMC Clinical Pharmacology 16 ( 1) 1 -1
1
2015
Induction of Angiotensin-Converting Enzyme and Activation of the Renin–Angiotensin System Contribute to 20-Hydroxyeicosatetraenoic Acid–Mediated Endothelial Dysfunction
Jennifer Cheng , Victor Garcia , Yan Ding , Cheng-Chia Wu
Arteriosclerosis, Thrombosis, and Vascular Biology 32 ( 8) 1917 -1924
44
2012
The Blood Pressure-Lowering Effect of 20-HETE Blockade in Cyp4a14(-/-) Mice Is Associated with Natriuresis.
Varunkumar Pandey , Victor Garcia , Ankit Gilani , Priyanka Mishra
Journal of Pharmacology and Experimental Therapeutics 363 ( 3) 412 -418
8
2017
Vascular characterization of mice with endothelial expression of cytochrome P450 4F2
Jennifer Cheng , Matthew L. Edin , Samantha L. Hoopes , Hong Li
The FASEB Journal 28 ( 7) 2915 -2931
23
2014
Androgen-sensitive hypertension associated with soluble guanylate cyclase-α1 deficiency is mediated by 20-HETE
Ana C Dordea , Sara Vandenwijngaert , Victor Garcia , Robert ET Tainsh
American Journal of Physiology-heart and Circulatory Physiology 310 ( 11)
9
2016
CYP4A/20-HETE regulates ischemia-induced neovascularization via its actions on endothelial progenitor and preexisting endothelial cells.
Li Chen , Samantha Tang , Frank F Zhang , Victor Garcia
American Journal of Physiology-heart and Circulatory Physiology 316 ( 6)
5
2019
Unbiased proteomics identifies plasminogen activator inhibitor-1 as a negative regulator of endothelial nitric oxide synthase.
Victor Garcia , Eon Joo Park , Mauro Siragusa , Florian Frohlich
Proceedings of the National Academy of Sciences of the United States of America 117 ( 17) 9497 -9507
1
2020
20-HETE and blood pressure regulation: clinical implications.
Cheng-Chia Wu , Tanush Gupta , Victor Garcia , Yan Ding
Cardiology in Review 22 ( 1) 1 -12
143
2014
20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension
Yan Ding , Cheng-Chia Wu , Victor Garcia , Irina Dimitrova
American Journal of Physiology-renal Physiology 305 ( 5) 753
18
2013
20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension.
Victor Garcia , Ankit Gilani , Brian Shkolnik , Varunkumar Pandey
Circulation Research 120 ( 11) 1776 -1788
109
2017
GATA6 reporter gene reveals myocardial phenotypic heterogeneity that is related to variations in gap junction coupling
Mathieu C. Rémond , Grazia Iaffaldano , Michael P. O'Quinn , Nadejda V. Mezentseva
American Journal of Physiology-heart and Circulatory Physiology 301 ( 5)
14
2011
20-HETE interferes with insulin signaling and contributes to obesity-driven insulin resistance.
Ankit Gilani , Kevin Agostinucci , Sakib Hossain , Jonathan V. Pascale
Prostaglandins & Other Lipid Mediators 152 106485 -106485
18
2021
Vascular actions of 20-HETE.
Samantha L. Hoopes , Victor Garcia , Matthew L. Edin , Michal L. Schwartzman
Prostaglandins & Other Lipid Mediators 120 9 -16
69
2015