High sensitivity assays for docetaxel and paclitaxel in plasma using solid-phase extraction and high-performance liquid chromatography with UV detection.

作者: Anders Andersen , David J Warren , Paal F Brunsvig , Steinar Aamdal , Gunnar B Kristensen

DOI: 10.1186/1472-6904-6-2

关键词: Therapeutic indexPharmacologyDetection limitPaclitaxelChromatographySolid phase extractionDocetaxelChemistryHigh-performance liquid chromatographyPharmacokineticsTaxane

摘要: … The majority of methods for both paclitaxel and docetaxel are based on the principles for … utilized UV absorbance. Later on the development of an HPLC method for docetaxel was …

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