Rapid high-performance liquid chromatographic determination of docetaxel (Taxotere) in plasma using liquid–liquid extraction

作者: J Ciccolini , J Catalin , M.F Blachon , A Durand

DOI: 10.1016/S0378-4347(01)00238-9

关键词: ChemistryExtraction (chemistry)High-performance liquid chromatographyDetection limitPaclitaxelDocetaxelChromatographyLiquid–liquid extractionStandard curveQuantitative analysis (chemistry)

摘要: … After adding an internal standard (paclitaxel, Taxol), plasma was extracted following a simple liquid–liquid extraction with diethyl ether. Extraction efficiency averaged 95% for docetaxel. …

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