Metabolic and Hormonal Alterations in Cats with Hepatic Lipidosis

摘要: Hepatic lipidosis in cats is a commonly diagnosed hepatobiliary disease of unknown cause. The purpose this prospective study was to characterize the blood hormone and lipid status with hepatic lipidosis, compare that other types liver control cats. Twenty-three were assigned 1 2 groups on basis cytopathologic or histopathologic examination liver: group 1, (n = 18); 2, cholangiohepatitis 5). Ten healthy young adult used as controls. Food withheld from animals for 24 hours before collection. Concentrations plasma glucagon serum insulin, cortisol, thyroxine, triglycerides, cholesterol, phospholipids, nonesterified fatty acids (NEFAs) determined all cats, addition routine hematologic biochemical testing. Cats had higher NEFA concentrations than (P < .05). cholesterol phospholipid those .05); their .05), but not different lipidosis. Serum insulin significantly diseased neither nor ratio among disease. high concentration NEFAs suggests at least factor pathogenesis syndrome may involve regulation hormone-sensitive lipase.