Analysis of Human Genetic Variations Using DNA Sequencing
作者： Gregory A. Hawkins
DOI: 10.1016/B978-0-12-803077-6.00005-9
关键词: Genomics 、 Biology 、 Massive parallel sequencing 、 Shotgun sequencing 、 DNA sequencing 、 Genetics 、 Exome sequencing 、 Whole genome sequencing 、 Cancer genome sequencing 、 Deep sequencing
摘要: Abstract Genetic mutations, also termed genetic variations or polymorphisms, alter protein production and are the primary drivers of diseases. DNA sequencing is gold standard for identifying variations, has more recently become a tool that allows rapid analysis whole genomes targeted small portion human genome contains genes. This chapter will focus on use two methods to identify in genome: Sanger next-generation sequencing.
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