Impact of spinal cord compression from intradural and epidural spinal tumors on perioperative symptoms-implications for surgical decision making.

摘要: Spinal cord or cauda equina compression (SCC) is an increasing challenge in clinical oncology due to a higher prevalence of long-term cancer survivors. Our aim was determine the relevance SCC regarding patient outcome depending on different tumor entities and their anatomical localization (extradural/intradural/intramedullary). We retrospectively analyzed 230 patients surgically treated for SCC. Preoperative status pain neurological impairment were correlated degree compression, location, early as well short-term follow-up parameters. Interestingly, we did not observe any differences between intradural-extramedullary compared extradural tumors. Unilaterally localized tumors likely present with (72.9 %, p < 0.01), whereas concentric growth associated motor deficits (41.0 %, p < 0.01, primary symptom, 49.3 % admission, p < 0.05). In tumors, pattern diffuse (40.5 % vs. 17.5 unilateral disease, resulted (61.4 % local axial radicular, p < 0.01). Diffuse pain, without sensory deficit, progressive cervical localization, stenosis identified beneficial improvement (p < 0.05). Notably, 29 % unchanged 30.8 % neurologic function at day 7 postoperative improved during (p < 0.001). data demonstrate that preoperative anatomy closely related presenting symptoms outcome. The detailed analysis elucidates biology might thereby aid determining which will benefit from surgery.