High Frequency of BRAFV600E Mutation in Acquired Nevi and Small Congenital Nevi, but Low Frequency of Mutation in Medium-Sized Congenital Nevi

作者: Nami Ichii-Nakato , Minoru Takata , Shuko Takayanagi , Shiho Takashima , Jingrong Lin

DOI: 10.1038/SJ.JID.5700366

关键词: Laser capture microdissectionMicrodissectionMutation (genetic algorithm)PathogenesisPoint mutationPathologyGlabrous skinNevusBiologyOncogene

摘要: To investigate whether the frequency of the BRAF V600E (V-raf murine sarcoma virus oncogene homolog B1) mutation in melanocytic nevi is associated with sun exposure patterns, we …

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