Potential nephroprotective effects of resveratrol in drug induced nephrotoxicity: a narrative review of safety and efficacy data

摘要: Drug induced nephrotoxicity commonly occurs in hospitalized patients and sometimes may complicate treatment outcome, especially critically ill patients. No universal prophylactic agent is available yet to protect against drug related nephrotoxicity. Many modalities have been applied with different successes. Polyphenolic compounds such as resveratrol used both in-vitro vivo prevent Resveratrol several antioxidant, antiplatelet nitric oxide releasing properties preclinical studies. In this review, we discuss recent studies that evaluated protective effects, the mechanism of action safety issues on