The effect of chronic kidney disease on lipid metabolism.

作者: Neris Dincer , Tuncay Dagel , Baris Afsar , Adrian Covic , Alberto Ortiz

DOI: 10.1007/S11255-018-2047-Y

关键词: High-density lipoproteinRenal functionPCSK9NephrologyGastroenterologyMedicineDiabetes mellitusKidney diseaseInternal medicineVery low-density lipoproteinDyslipidemia

摘要: The major cause of death among chronic kidney disease patients is cardiovascular diseases. Cardiovascular and are interrelated increase the severity each other. Dyslipidemia one causes along with diabetes hypertension. relationship between dyslipidemia reciprocal. known to be a risk factor for alterations on lipoprotein profile, defined as "dyslipidemic profile" patients. Increased triglyceride, very low density oxidized well decreased high changes in composition lipoproteins contribute profile." Treatment strategies targeting could prevent Current therapy based patient function consist mainly statins. This review focuses effects profile how this may impact novel therapeutic approaches risk.

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